Rhegmatogenous Retinal Detachment in Labrador Retrievers

Canine retinal surgery

“…Fortunately, PVR is not commonly seen in most cases of canine RRD. It has been reported in the Labrador Retriever breed with oculoskeletal dysplasia 32 . We have encountered it in several breeds, mainly in long‐standing detachments.…”

“…It has been reported in the Labrador Retriever breed with oculoskeletal dysplasia. 32 We have encountered it in several breeds, mainly in long-standing detachments. If PVR is present, there is a poorer prognosis for surgical success, as it is probably the most common cause of reattachment failure in humans and dogs.…”

Retinal dysplasia inAmerican pit bull terriers – phenotypic characterization and breeding study

“…In some forms, there may be other concurrent ocular developmental disorders such as persistent hyperplastic primary vitreous, congenital cataracts, microphthalmia, or coloboma . Syndromic forms have also been reported, with affected dogs having concurrent nonocular abnormalities such as dwarfism with skeletal dysplasia, as occurs in ocular skeletal dysplasia (OSD) . OSD has been studied in detail in the labrador retriever and samoyed breeds in which it is termed dwarfism with retinal dysplasia (drd) .…”

“…It has been suggested that animals heterozygous for the particular causal gene mutation have either no detectable phenotype, or a relatively mild ocular phenotype ranging from vitreous strands to focal or multifocal RD lesions to larger geographic lesions but have a normal appendicular skeleton. However, the homozygous animals have a severe ocular phenotype, usually with retinal detachment, vitreal dysplasia, cataracts, and short‐limbed dwarfism . Identification of the gene mutation allows the incidence of an ocular phenotype in dogs heterozygous for the causal mutation to be investigated .…”

“…14,15,39 Syndromic forms have also been reported, with affected dogs having concurrent nonocular abnormalities such as dwarfism with skeletal dysplasia, as occurs in ocular skeletal dysplasia (OSD). [31][32][33]44 OSD has been studied in detail in the labrador retriever and samoyed breeds in which it is termed dwarfism with retinal dysplasia (drd). The causal gene mutations in the two breed have been identified in the Collagen 9A3 and 9A2 genes, respectively.…”