Rhegmatogenous Retinal Detachment

Colucciello, Michael

doi:10.3810/psm.2009.06.1710

Cited by 16 publications

(13 citation statements)

References 25 publications

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“…Em consequência disso, pode haver perda importante e potencialmente irreversível da acuidade visual, caso não haja detecção e intervenção precoces. A incidência anual de DRR foi relatada em 12 casos a cada 100.000 pessoas e a maior parte dos casos ocorre em pessoas entre 40 e 70 anos de idade 3 . As taxas de incidência de descolamento não traumático são similares entre ambos os sexos, no entanto, existe uma preponderância pelo sexo feminino, devido as mulheres representarem maior parte na população mundial 4 .…”

Section: Introductionunclassified

Descolamento De Retina Macular Sem Queixas Visuais: A Importância Do Exame Oftalmológico De Rotina

Pinto¹,

Oliveira²,

Neto³

2021

RBM

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Objetivo: os autores têm objetivo de relatar um caso de descolamento de retina de apresentação atípica com potencial desfecho visual desfavorável detectado através de um exame de rotina.Método: relato de caso e revisão de literatura.Resultado: WBP, 42 anos, feminino procurou oftalmologista para exame de rotina sem queixas visuais. Exame físico: acuidade visual com correção 20/20 em ambos os olhos. Avaliação fundoscópica: descolamento de retina rematogênico na topografia macular à 1 mm da fóvea. Paciente foi submetida à introflexao escleral e endofotocoagulação a laser. Os procedimentos foram bem sucedidos, sem complicações pós-operatórias. No momento, segue em acompanhamento ambulatorial anual sem outras queixas oftalmológicas.Conclusão: em suma, este caso evidencia a importância da avaliação oftalmológica de rotina para diagnosticar e intervir precocemente em patológicas oculares graves e silenciosas, a fim de proporcionar melhor prognóstico visual aos pacientes.

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Section: Introductionunclassified

Descolamento De Retina Macular Sem Queixas Visuais: A Importância Do Exame Oftalmológico De Rotina

Pinto¹,

Oliveira²,

Neto³

2021

RBM

View full text Add to dashboard Cite

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“…14 The most common type of RD is rhegmatogenous RD, which is caused mainly by retinal breaks owing to vitreous traction. 15 Although vitrectomy surgery has contributed greatly to the successful treatment of severe retinal diseases, including RD, it is difficult to recover all cases of RD completely. Patients with severe and/or long-standing RD or those with unsuccessful surgical treatment tend to suffer PVR.…”

Section: Introductionmentioning

confidence: 99%

Biological Involvement of MicroRNAs in Proliferative Vitreoretinopathy

Kaneko

Terasaki

2017

Trans. Vis. Sci. Tech.

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Even with a high surgical success rate for retinal detachment and proliferative vitreoretinopathy (PVR) supported by the robust improvement in vitrectomy surgery and its related devices, certain questions still remain for the pathogenesis and treatment of PVR. One of the important biological events in PVR is epithelial–mesenchymal transition (EMT) of the retinal pigment epithelial (RPE) cells. MicroRNAs are noncoding, small, single-strand RNAs that posttranscriptionally regulate gene expression and have essential roles in homeostasis and pathogenesis in many diseases. Recently, microRNAs also had a critical role in EMT in many tissues and cells. One main purpose of this brief review is to describe the knowledge obtained from microRNA research, especially concerning vitreoretinal diseases. In addition, the potential role of microRNAs in prevention of PVR by regulating EMT in RPE cells is described. Understanding microRNA involvement in PVR could be helpful for developing new biological markers or therapeutic targets and reducing the rate of visual disability due to PVR.

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“…Retinal detachment (RD) is a serious disease that can cause blindness [ 1 ]. The incidence of RD was reported to be 0.6–1.8 per 10000 people [ 2 ], and the most common type of RD is rhegmatogenous RD (RRD), which is mainly caused by retinal breaks owing to vitreous traction [ 3 ]. Despite recent advances in surgical methods and technology that have improved the rates of structural recovery following surgery, [ 4 , 5 ] it is difficult to recover all cases of RRD completely.…”

Section: Introductionmentioning

confidence: 99%

Correlation between miR-148 Expression in Vitreous and Severity of Rhegmatogenous Retinal Detachment

Tsunekawa

Kaneko

Takayama

et al. 2017

BioMed Research International

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Purpose. We had earlier reported positive hsa-miR-148a-3p expression in eyes with rhegmatogenous retinal detachment (RRD) and its involvement in the epithelial-mesenchymal transition of retinal pigment epithelium in vitro. Here we investigated the association of hsa-miR-148a-3p expression levels in the vitreous fluid of patients with RRD with severity of RRD. Methods. The hsa-miR-148a-3p expression levels in the vitreous fluid, range (degree) of retinal detachment (RD), and pixels of retinal break were measured in 27 eyes with RRD. The association of hsa-miR-148a-3p expression levels with other factors was evaluated by multiple regression analysis. Results. The hsa-miR-148a-3p expression levels, time from onset of RRD to vitrectomy, range of RD, and pixels of retinal breaks were 23.68 ± 43.00, 12.07 ± 15.36 days, 155.85 ± 86.67 degrees, and 37000 ± 67100 pixels, respectively. Five eyes with RRD had vitreous hemorrhage preoperatively. The hsa-miR-148a-3p expression levels were significantly associated with pixels of retinal breaks (β = 0.699) and the time from onset of RRD to vitrectomy (β = 0.358) but not with the range of RD or presence of vitreous hemorrhage. Conclusion. The hsa-miR-148a-3p expression levels in the vitreous fluid were significantly associated with the size of retinal break and disease duration.

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Rhegmatogenous Retinal Detachment

Cited by 16 publications

References 25 publications

Descolamento De Retina Macular Sem Queixas Visuais: A Importância Do Exame Oftalmológico De Rotina

Descolamento De Retina Macular Sem Queixas Visuais: A Importância Do Exame Oftalmológico De Rotina

Biological Involvement of MicroRNAs in Proliferative Vitreoretinopathy

Correlation between miR-148 Expression in Vitreous and Severity of Rhegmatogenous Retinal Detachment

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