Rhizome Saponins ofPanax pseudo-ginsengsubsp.himalaicusand its var.bipinnatifidus1,2

Yn, Shukla

doi:10.1055/s-2006-962042

Cited by 4 publications

(1 citation statement)

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“…bipinnatifidus [ 14 ], while G-Rb2, G-Rb1, and G-Rd have been reported in P. pseudoginseng var. bipinnatifidus [ 24 ]. Other identified markers, particularly OT-type saponins including M-R2, V-R2, V-R13, and M-R1 thus far have been reported only in P. vietnamensis species.…”

Section: Resultsmentioning

confidence: 99%

Untargeted Metabolomics Approach for the Differentiation between Panax vietnamensis var. vietnamensis and Panax vietnamensis var. fuscidiscus

Nguyen,

Phan,

Huynh

et al. 2023

Metabolites

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Panax vietnamensis var. vietnamensis (PVV) and Panax vietnamensis var. fuscidiscus (PVF) both belong to Panax vietnamensis species and are chemically and morphologically similar, making it hard to distinguish for the consumer. Herein, 42 PVF and 12 PVV samples were collected in Quang Nam and Lai Chau Province, respectively, and subsequently characterized by ITSr-DNA sequence data to verify their origins. Next, untargeted metabolomics combined with multivariate statistical analysis was developed to differentiate PVV and PVF. The metabolic profiles of PVV and PVF were found to be distinct and classified well using Partial Least-Squares Discriminant Analysis (PLS-DA) in the training set. Among them, seven ginsenosides were of high abundance in PVV, while six were of high abundance in PVF. Next, the test set was used to validate 13 putative differential markers found in the training set, illustrating a complete match with the expression patterns of these ginsenosides in the training set. Finally, PLS-DA and linear Support Vector Machine models both indicated distinct ginsenoside profiles of PVV and PVF without misclassification in the test set. Conclusively, the developed untargeted metabolomics approach might serve as a powerful tool for the authentication of PVV and PVF at the metabolome level.

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Section: Resultsmentioning

confidence: 99%

Untargeted Metabolomics Approach for the Differentiation between Panax vietnamensis var. vietnamensis and Panax vietnamensis var. fuscidiscus

Nguyen,

Phan,

Huynh

et al. 2023

Metabolites

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Constituents of the fruit of Randia siamensis, biological activity of saponin pseudoginsenoside-RT1

Jansakul

Intarit

Itharat

et al. 1999

Advances in Plant Glycosides, Chemistry and Biology, Proceedings of the International Symposium in Plant Glycosides

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Research progress on naturally-occurring and semi-synthetic ocotillol-type ginsenosides in the genus Panax L. (Araliaceae)

Niu

Luo

et al. 2021

Chinese Journal of Natural Medicines

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Rhizome Saponins ofPanax pseudo-ginsengsubsp.himalaicusand its var.bipinnatifidus^1,2

Abstract: In our previous communications, we have characterized 15 saponins (1-3) and several other constituents (4, 5) from the rhizomes of P. pseudo-ginseng Wall.

Cited by 4 publications

References 1 publication

Untargeted Metabolomics Approach for the Differentiation between Panax vietnamensis var. vietnamensis and Panax vietnamensis var. fuscidiscus

Untargeted Metabolomics Approach for the Differentiation between Panax vietnamensis var. vietnamensis and Panax vietnamensis var. fuscidiscus

Constituents of the fruit of Randia siamensis, biological activity of saponin pseudoginsenoside-RT1

Research progress on naturally-occurring and semi-synthetic ocotillol-type ginsenosides in the genus Panax L. (Araliaceae)

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