Rickettsia sp. and Anaplasma spp. in Haemaphysalis longicornis from Shandong province of China, with evidence of a novel species “Candidatus Anaplasma Shandongensis”

Lu, Miao; Meng, Chao; Li, Yilin; Zhou, Guangyi; Wang, Lin; Xu, Xiaoyu; Li, Na; Ji, Yu; Tian, Jingkui; Wang, Wen; Li, Kun

doi:10.1016/j.ttbdis.2022.102082

Cited by 8 publications

(5 citation statements)

References 37 publications

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“…H. longicornis is also recognized as potentially transmitting other pathogens like Borrelia spp., Anaplasma spp., and Ehrlichia spp. [ 27 , 28 , 29 ]. Our detection of these four pathogens lends credence to their potential role as vectors.…”

Section: Discussionmentioning

confidence: 99%

Tick Diversity and Pathogen Transmission in Daejeon, Korea: Implications from Companion Animals and Walking Trails

Seo,

Kim,

Lim

et al. 2024

Veterinary Sciences

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With the ongoing global warming-induced climate change, there has been a surge in vector-borne diseases, particularly tick-borne diseases (TBDs). As the population of companion animals grows, there is growing concern from a One Health perspective about the potential for these animals to spread TBDs. In this study, ticks were collected from companion animals and the surrounding environment in Daejeon Metropolitan City, Korea, using flagging and dragging, and CO2 trap methods. These ticks were then subjected to conventional (nested) PCR for severe fever with thrombocytopenia syndrome virus (SFTSV), Anaplasma spp., Ehrlichia spp., and Borrelia spp. We identified a total of 29,176 ticks, consisting of three genera and four species: H. longicornis, H. flava, I. nipponensis, and A. testudinarium. Notably, H. longicornis was the predominant species. The presence of A. testudinarium suggested that the species traditionally found in southern regions are migrating northward, likely as a result of climate change. Our PCR results confirmed the presence of all four pathogens in both companion animals and the surrounding environment, underscoring the potential for the indirect transmission of tick-borne pathogens to humans through companion animals. These findings emphasize the importance of the ongoing surveillance of companion animals in the management and control of TBDs.

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Section: Discussionmentioning

confidence: 99%

Tick Diversity and Pathogen Transmission in Daejeon, Korea: Implications from Companion Animals and Walking Trails

Seo,

Kim,

Lim

et al. 2024

Veterinary Sciences

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“…2 . Haemaphysalis longicornis is the tick species on which the most studies have been conducted and for which A. capra has been detected the most (Guo et al 2018 ; Lu et al 2023 ; Qin et al 2018 ; Seo et al 2020 ; Sun et al 2015 ; Teng et al 2023 ; Yan et al 2021 ). In much more limited work, A. capra was detected in H. ginghainensis (Han et al 2019 ; Yang et al 2016 ), Ixodes persulcatus (Li et al 2015 ), I. kashmiricus (Numan et al 2023 ), Rhipicephalus sanguineus (unpublished data, GenBank; OK091153), R. microplus ( Addo et al 2023 ; Guo et al 2018 , 2019 ) Dermacontor nuttali, D. everestianus , and D. abaensis (Han et al 2019 ).…”

Section: The Hosts Of Anaplasma Capramentioning

confidence: 99%

“…The positivity rate in ticks is quite variable. It was detected in I. persulcatus at 3.0% (Li et al 2015 ), in H. longicornis at 0.43–63.27% (Guo et al 2018 ; Lu et al 2023 ; Seo et al 2020 ; Sun et al 2015 ; Teng et al 2023 ; Yan et al 2021 ;), in H. qinghaiensis at 4.5–5.8% (Han et al 2019 ; Yang et al 2016 ), in R. microplu s at 0.81–40.4% positive rates (Addo et al 2023 ; Guo et al 2018 , 2019 ). Almost all of the studies on ticks were conducted in China, where A. capra was first detected and where most studies were conducted on vertebrates.…”

Section: The Hosts Of Anaplasma Capramentioning

confidence: 99%

“…Almost all of the studies on ticks were conducted in China, where A. capra was first detected and where most studies were conducted on vertebrates. A very high positivity rate (63.27%) was determined in H. longicornis collected from goats in China (Lu et al 2023 ). On the other hand, H. longicornis is the most prevalent tick species in China and is especially parasitized in sheep (Teng et al 2023 ).…”

Section: The Hosts Of Anaplasma Capramentioning

confidence: 99%

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Anaplasma capra: a new emerging tick-borne zoonotic pathogen

Altay,

Erol,

Sahin

2024

Vet Res Commun

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The genus Anaplasma includes A. marginale, A. centrale, A. bovis, A. ovis, A. platys, and A. phagocytophilum transmitted by ticks, some of which are zoonotic and cause anaplasmosis in humans and animals. In 2012, a new species was discovered in goats in China. In 2015, the same agent was detected in humans in China, and it was provisionally named Anaplasma capra, referring to 2012. The studies conducted to date have revealed the existence of A. capra in humans, domestic animals, wild animals, and ticks from three different continents (Asia, Europe, and Africa). Phylogenetic analyses based on gltA and groEL sequences show that A. capra clearly includes two different genotypes (A. capra genotype-1 and A. capra genotype-2). Although A. capra human isolates are in the genotype-2 group, goat, sheep, and cattle isolates are in both groups, making it difficult to establish a host genotype-relationship. According to current data, it can be thought that human isolates are genotype-2 and while only genotype-1 is found in Europe, both genotypes are found in Asia. Anaplasma capra causes clinical disease in humans, but the situation is not yet sufficient to understand the zoonotic importance and pathogenicity in animals. In the present review, the history, hosts (vertebrates and ticks), molecular prevalence, pathogenic properties, and genetic diversity of A. capra were evaluated from a broad perspective.

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“…All the ticks were observed by a stereoscopic microscope (Olympus SZX 16, Olympus Corporation, Tokyo, Japan). For further con rmation, ticks were randomly selected from each species, and the COI (Cytochrome oxidase I) sequences were PCR ampli ed and sequenced (primers shown in reference [7]) after DNA extraction.…”

Section: Sample Collection and Dna Extractionmentioning

confidence: 99%

Molecular surveillance reveals a potential hotspot of tick-borne disease in Hulunbuir City, Inner Mongolia

Tian,

Liu,

Zhao

et al. 2023

Preprint

Self Cite

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A molecular surveillance of tick-borne diseases was performed in Hulunbuir City, Inner Mongolia. A total of 149 ticks including three species (Ixodes persulcatus, Haemaphysalis concinna, and Dermacentor silvarum) were collected. As many as 11 tick-borne bacterial pathogens were identified in them. Some of them have high positive rates. For example, Candidatus Rickettsia tarasevichiae was detected with a high prevalence of 72.48%, while Candidatus Lariskella sp. was detected in 31.54% of ticks. For both Rickettsia raoultii and Anaplasma phagocytophilum, two distinct genotypes were identified based on their phylogenetic trees based on 16S rRNA, gltA, and groEL sequences. Remarkable genetic diversity was also observed for 16S and flaB genes of Borreliella garinii, an agent of Lyme disease. Rickettsia heilongjiangensis causing Far-Eastern spotted fever (2.68%, 4/149), Ehrlichia muris causing human ehrlichiosis (4.70%, 7/149), Borrelia miyamotoi causing relapsing fever (2.01%, 3/149), and Borreliella afzelii causing Lyme disease (2.01%, 3/149) were also detected. Additionally, a previously uncharacterized Anaplasma species closely related to Anaplasma ovis was identified. Herein we name it “Candidatus Anaplasma mongolica”. Based on these results, we propose that Hulunbuir City, as well as the northeast part of Inner Mongolia, might be a potential hotspot of tick-borne diseases.

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Rickettsia sp. and Anaplasma spp. in Haemaphysalis longicornis from Shandong province of China, with evidence of a novel species “Candidatus Anaplasma Shandongensis”

Cited by 8 publications

References 37 publications

Tick Diversity and Pathogen Transmission in Daejeon, Korea: Implications from Companion Animals and Walking Trails

Tick Diversity and Pathogen Transmission in Daejeon, Korea: Implications from Companion Animals and Walking Trails

Anaplasma capra: a new emerging tick-borne zoonotic pathogen

Molecular surveillance reveals a potential hotspot of tick-borne disease in Hulunbuir City, Inner Mongolia

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