Right and Left Ventricular Diastolic Filling Parameters in Essential Hypertension

Akkoç, Azad; Uçaman, Berzal; Kaymak, Halil; Temamoğullari, Ali Vahip; İltümür, Kenan; Karadede, A. Aziz; Toprak, Nizamettin

doi:10.1177/021849239900700312

Cited by 9 publications

(2 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This decrease in E/A ratio and increase in E-wave deceleration time suggests impaired myocardial relaxation during diastole in hypertensive population which in accordance with the results of Azad Akkoc et al 20 , Verdecchia et al 12 and Akintunde et al 21 Increased IVRT i.e., the time taken by the left ventricular pressure to fall below left atrial pressure, suggests impaired myocardial relaxation. 22 The increase in IVRT in our study correlates with the study done by Akintunde et al 21 Hypertension exerts pressure overload on the heart.…”

Section: Discussionsupporting

confidence: 88%

Evaluation of diastolic function in hypertensive using echocardiography

Lavanya¹,

Singh

Sajja³

et al. 2015

Int J Res Med Sci

View full text Add to dashboard Cite

INTRODUCTIONHigh blood pressure is more prevalent in the general population. Hypertension significantly contributes to cardiovascular (CV) morbidity and mortality by causing substantial structural and functional adaptations, including diastolic dysfunction (DD), left ventricular hypertrophy (LVH), ventricular and vascular stiffness. Chronic hypertension is the most common cause of diastolic dysfunction and failure. Abnormalities of ventricular relaxation and the consequences of diastolic dysfunction may signify myocardial end-organ damage in patients who have hypertension which precede ventricular hypertrophy. 1,2Isolated diastolic dysfunction is impairment of isovolumetric ventricular relaxation and decreased compliance of the left ventricle. Symptomatic diastolic dysfunction is called diastolic heart failure. With diastolic dysfunction, heart meets the body's metabolic needs, whether at rest or during exercise, but at a higher filling pressure's. With mild dysfunction, late filling increases ABSTRACT Background: Heart failure is one of the most common causes of cardiovascular morbidity along with mortality and hypertension is the most common cause of cardiac failure. Recent studies have shown that isolated diastolic dysfunction very often accompanies hypertensive heart disease. Aims: The present study was conducted to identify the risk of cardiac failure in hypertensive individuals by evaluating diastolic function using mitral inflow velocities of echocardiography. Methods: Subjects attending cardiology outpatient department for master health check up with age between 25 to 80 years were selected. The procedure was explained and consent was obtained from the subjects. All the subjects underwent a detailed clinical examination. Height, weight and blood pressure of the subjects was measured and BMI was calculated. Two-dimensional Doppler echocardiographic examinations were performed with an ultrasonographic system (Philips iE 133 Echo Doppler). The student t test, chi square test and logistic regression analysis were used to find the influence of ejection fraction and heart rate on diastolic function. Results: The trans-mitral inflow parameters on Doppler echocardiography such as E wave deceleration time (DT), isovolumetric relaxation time (IVRT) and early to late transmitral peak flow velocities ratio (E/A) were significantly different in hypertensive subjects on treatment having normal ejection fraction, when compared to normotensive subjects. We observed a decrease in E/A ratio and increase in DT, IVRT with hypertension. Conclusions: From the present study it can be concluded that hypertension is significantly associated with diastolic dysfunction of heart, even in subjects with normal systolic function.

show abstract

Section: Discussionsupporting

confidence: 88%

Evaluation of diastolic function in hypertensive using echocardiography

Lavanya¹,

Singh

Sajja³

et al. 2015

Int J Res Med Sci

View full text Add to dashboard Cite

show abstract

“…Some authors reported that arterial hypertension was associated with increased pulmonary arterial pressure and pulmonary arteriolar resistance, which was not a consequence of impaired left ventricular function. 51,52 Olivari et al 51 performed hemodynamic evaluation of 33 hypertensive patients with blood pressure more than 180/100 mmHg and 14 normotensive controls, and found that pulmonary systolic, diastolic, and pulmonary wedge pressure were significantly increased in the hypertensive patients. However, other authors who performed noninvasive measurements of pulmonary blood pressure did not find any difference between the arterial hypertension and the controls.…”

Section: Pulmonary Circulation and Exercise In Arterial Hypertensionmentioning

confidence: 99%

Why is functional capacity decreased in hypertensive patients? From mechanisms to clinical studies

Tadić

Ivanović²

2014

Journal of Cardiovascular Medicine

View full text Add to dashboard Cite

The influence of arterial hypertension on functional capacity is poorly understood. Studies have shown that peak oxygen consumption has been reduced in hypertensive patients, but the mechanisms are unclear. Left ventricular systolic and diastolic dysfunction, as well as left ventricular hypertrophy, are associated with lower functional capacity in patients with arterial hypertension. Furthermore, some investigations found a significant relationship between right ventricular systolic function and functional capacity in the general population. The aim of this review was to summarize current knowledge about the mechanisms of reduced functional capacity in hypertensive patients, including the impact of systemic and pulmonary circulations, as well as the influence of the left and right ventricle on oxygen consumption. Additionally, we reviewed all clinical studies regarding functional capacity in the population with arterial hypertension.

show abstract

Rechter Ventrikel bei arterieller Hypertonie

Motz

2004

Internist

View full text Add to dashboard Cite

Left ventricular hypertrophy is the best known and most evident cardiac organ manifestation of arterial hypertension. However, only limited findings are available on function and structure of the right ventricle. The published studies show that the right ventricle is also affected in the course of hypertensive heart disease. Particularly hypertrophy of the right ventricular free wall, impaired right ventricular diastolic filling, elevated right ventricular filling pressure as well as impairment of right ventricular ejection fraction in the late phase of arterial hypertension were reported. Possible causes of these structural and functional changes of the right ventricle are (1) translation of the increased left ventricular filling pressure in the pulmonary circulation, (2) interaction of the right and left ventricle, and (3) systemic circulation of cytokines and growth hormones such as angiotensin II, aldosterone, and others.

show abstract

Right and Left Ventricular Diastolic Filling Parameters in Essential Hypertension

Cited by 9 publications

References 26 publications

Evaluation of diastolic function in hypertensive using echocardiography

Evaluation of diastolic function in hypertensive using echocardiography

Why is functional capacity decreased in hypertensive patients? From mechanisms to clinical studies

Rechter Ventrikel bei arterieller Hypertonie

Contact Info

Product

Resources

About