2001
DOI: 10.1016/s0735-1097(01)01305-5
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Right ventricular form and function after percutaneous atrial septal defect device closure

Abstract: Right heart morphology undergoes rapid improvement within one month of defect closure, with associated mechanoelectrical benefit. A small number of patients had persistent RV enlargement or pulmonary hypertension, or both, at one year. Our data support the application of transcatheter methods in achieving excellent hemodynamic and anatomic outcomes.

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Cited by 153 publications
(129 citation statements)
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“…Similar data have been reported more recently from device closure series. 47 The favorable impact of ASD device closure on clinical performance appears both more widespread and faster than that reported in the surgical literature. Brochu and colleagues 48 reported a 15% improvement in peak oxygen uptake at 6 months after device closure.…”
Section: Exercise Capacitymentioning
confidence: 98%
“…Similar data have been reported more recently from device closure series. 47 The favorable impact of ASD device closure on clinical performance appears both more widespread and faster than that reported in the surgical literature. Brochu and colleagues 48 reported a 15% improvement in peak oxygen uptake at 6 months after device closure.…”
Section: Exercise Capacitymentioning
confidence: 98%
“…25 Percutaneous closure of ASDs has been reported in nonrandomized uncontrolled fashion to be associated with improvement in right ventricular anatomy, function, and left ventricular interaction, as well as in exercise capacity as measured by cardiopulmonary exercise testing. 26,27 ASDs can be classified as ostium secundum, ostium primum, sinus venosus, and coronary sinus septal defects, depending on location in the interatrial septum. Occasionally, multiple defects can be observed, especially associated with a thin, hypermobile septum primum.…”
Section: Device Closure Interatrial Communicationsmentioning
confidence: 99%
“…11,12 It is apparent that ASD closure eliminates the left-to-right shunt with the resultant reduction in volume loading of the right atrium and right ventricle, which should reduce the mechanical work of the right ventricle. A reduction in volume would, however, alter RV geometry, and acute changes in RV geometry may worsen RV function.…”
Section: Asd Closure and Rv Functionmentioning
confidence: 99%