Rilonacept (IL-1 TRAP) for treatment of colchicine resistant familial mediterranean fever (FMF): a randomized, multicenter double-blinded, alternating treatment trial

Hashkes, PJ; Spalding, SJ; Eh, Giannini; Huang, Bin; Park, G; Ks, Barron; Weisman, MH; Pashinian, Noune; Reiff, A.; Samuels, Jonathan; Wright, Dowain A.; Kastner, DL; Lovell, DJ

doi:10.1186/1546-0096-9-s1-o38

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Interventions for reducing inflammation in familial Mediterranean fever

et al. 2015

Cochrane Database of Systematic Reviews

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There were limited randomized controlled studies assessing interventions for people with familial Mediterranean fever. Based on the evidence, colchicine appears to reduce the number of people experiencing attacks; however, only a few low-quality randomized controlled studies contributed data for analysis. Further randomized controlled studies examining active interventions, not only colchicine, are necessary before a comprehensive conclusion regarding the efficacy and safety of interventions for reducing inflammation in familial Mediterranean fever can be drawn.

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Interventions for reducing inflammation in familial Mediterranean fever

et al. 2015

Cochrane Database of Systematic Reviews

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Interventions for reducing inflammation in familial Mediterranean fever

Liu

et al. 2018

Cochrane Database of Systematic Reviews

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Analysis 1.1. Comparison 1 Colchicine versus placebo, Outcome 1 Number of participants experiencing an attack.. Analysis 2.1. Comparison 2 Rilonacept versus placebo, Outcome 1 Number of participants experiencing an attack.. Analysis 3.1. Comparison 3 ImmunoGuard™ versus placebo, Outcome 1 Acute phase response.. .. .. .. Analysis 4.1. Comparison 4 Anakinra versus placebo, Outcome 1 Number of participants experiencing an attack.. Analysis 4.2. Comparison 4 Anakinra versus placebo, Outcome 2 Drug-related adverse events. .

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Interventions for reducing inflammation in familial Mediterranean fever

Yin

Tian

et al. 2022

Cochrane Database of Systematic Reviews

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Rilonacept (IL-1 TRAP) for treatment of colchicine resistant familial mediterranean fever (FMF): a randomized, multicenter double-blinded, alternating treatment trial

Cited by 5 publications

References 0 publications

Interventions for reducing inflammation in familial Mediterranean fever

Interventions for reducing inflammation in familial Mediterranean fever

Interventions for reducing inflammation in familial Mediterranean fever

Interventions for reducing inflammation in familial Mediterranean fever

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