Ring enhancing intracranial lesion responding to antituberculous treatment in an HIV-infected patient

Abstract

Cerebral tuberculomas constitute a major differential diagnosis of cerebral toxoplasmosis in human immunodeficiency virus (HIV)-infected patients in developing countries. We report the case of a 34-year old woman co-infected with HIV and possible disseminated tuberculosis (hepatitis, lymphadenopathy, and pleural effusion) who presented a large and solitary intracranial mass lesion. Despite extensive diagnostic efforts, including brain, ganglionar, and liver biopsies, no definitive diagnosis was reached. However, a trial with first-line antituberculous drugs led to a significant clinical and radiological improvement. Atypical presentations of cerebral tuberculomas should always be considered in the differential diagnosis of intracranial mass lesions in HIV-infected patients and a trial with antituberculous drugs is a valuable strategy to infer the diagnosis in a subset of patients.

Application of brain multi-b-value diffusion-weighted imaging (DWI) in adolescent orphans from AIDS families

“…4 MRI technology and functional MRI technology have broad application in the diagnosis of HIV-infection-related diseases. [5][6][7][8][9][10][11][12][13] Advanced MRI techniques include perfusionweighted imaging (PWI), diffusion tensor imaging, MR spectroscopy (MRS) and diffusion-weighted imaging (DWI ) is widely used in the diagnosis, prognosis and treatment assessment of diseases. [16][17][18] Recently, scholars have studied HIV-positive patients with conventional DWI 9,11,13 and have made certain achievements.…”