The estimate of seismic lithosphere thickness in Siberia remains controversial in spite of long-range controlledesource data available from peaceful nuclear explosions (PNE). Published models of layered upper mantle based on this evidence fail to unambiguously constrain the asthenospheric depth. The observed velocity changes may be due either to vertical layering or to lateral heterogeneity, which are difficult to discriminate because of large (1000 km) PNE spacing. Among the upper mantle models, obtained with reference to Moho velocities derived from higher-resolution chemical explosion data, we focus especially on lateral density heterogeneity. The model reveals three velocity layers, with velocities 8.0e8.5 km/s in Layer 1, 8.6e8.7 km/s in Layer 2, and~8.5 km/s in Layer 3. Layers 2, which varies strongly in thickness, may consist of dense eclogite, judging by the high velocities. Its base may correspond to the base of the lithosphere underlain by the lower-velocity asthenospheric material of Layer 3.The lateral variations in velocity within Layer 1 and in thickness of Layer 2 correlate with major tectonic units: the West Siberian basin, the Tunguska basin with the PermianeTriassic continental flood basalts (the large igneous province of Siberian Traps), as well as the Vilyui basin and the Yakutian kimberlite province. Isostasy in the West Siberian and Vilyui basins results in thick sediments and thin crust, while the large depths of the basement and the intraecrustal discontinuity in the Tunguska basin isostatically compensate the elevated surface topography due to voluminous lavas. The magmatism left its imprint in the mantle as an attenuated "eclogitic layer" beneath the Tunguska basin. However, the available data are still insufficient to understand the exact causes of this attenuation, because mantle conditions may have changed during the elapsed 250 m.y. since then.