2001
DOI: 10.1159/000049879
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Rising PSA after a Radical Treatment

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Cited by 33 publications
(16 citation statements)
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“…Lymph node dissection boundries extended proximally from the common iliac bifurcation, laterally to the medial aspect of the external iliac artery, distally to the lymph node of Cloquet, and included the hypogastric and obturator fossae. 11 Median follow-up in this series for the 180 N0 patients was 12.7 years (range, 1.5 years to 19.1 years), and for the 94 Nϩ patients median follow-up was 13.6 years (range, 0.9 years to 19.7 years); for the entire cohort of 274 patients, median follow-up was 12.9 years (Table 2). One hundred eighty six of 283 patients (66%) were N0 by routine histology, 94 of 283 patients (33%) were node positive (Nϩ), and lymph node status was not available for three patients.…”
Section: Patient Populationmentioning
confidence: 76%
“…Lymph node dissection boundries extended proximally from the common iliac bifurcation, laterally to the medial aspect of the external iliac artery, distally to the lymph node of Cloquet, and included the hypogastric and obturator fossae. 11 Median follow-up in this series for the 180 N0 patients was 12.7 years (range, 1.5 years to 19.1 years), and for the 94 Nϩ patients median follow-up was 13.6 years (range, 0.9 years to 19.7 years); for the entire cohort of 274 patients, median follow-up was 12.9 years (Table 2). One hundred eighty six of 283 patients (66%) were N0 by routine histology, 94 of 283 patients (33%) were node positive (Nϩ), and lymph node status was not available for three patients.…”
Section: Patient Populationmentioning
confidence: 76%
“…While men with localized prostate cancer are treated with the curative intent, approximately 40% of patients will experience a detectable rise in the serum PSA level (biochemical failure) within 10 years from the primary treatment (3). Locally recurrent cancer is eventually detected in about 25–35%, metastatic disease only in about 20–25% and both local recurrence and metastatic disease in 45–55% of men with biochemical failure (4). While most men with metastatic disease respond to androgen deprivation therapy, many will develop castrate-resistant state within 1–3 years with the hallmark of tumor growth despite castrate levels of serum androgens (5, 6).…”
Section: Introductionmentioning
confidence: 99%
“…14 Locally recurrent cancer is eventually detected in approximately 25% to 35%, metastatic disease only in approximately 20% to 25%, and both local recurrence and metastatic disease in 45% to 55% of men with biochemical failure. 1,15 …”
Section: Discussionmentioning
confidence: 99%