Risk Analysis of Falls in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Ueki, Satoko; Ikegame, Kazuhiro; Kozawa, Mariko; Miyamoto, Junko; Mori, Ryuji; Ogawa, Hiroyasu

doi:10.1188/14.cjon.396-399

Cited by 19 publications

(20 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some previous studies reported that falls often occurred in the patients' rooms (1,3,(13)(14)(19)(20). In our study, 79.2% of falls occurred in patients' rooms, and !…”

Section: Discussionsupporting

confidence: 49%

Falls among Hospitalized Patients in an Acute Care Hospital: Analyses of Incident Reports

et al. 2018

View full text Add to dashboard Cite

: Falls cause injuries such as fractures, skin lacerations, bleeding, and head injury, and could result in more severe medical conditions in hospitalized patients. We retrospectively investigated the incidence and characteristics of falls among hospitalized patients in an acute care hospital from incident reports by hospital staff between January and June 2013. There were 154 falls in 135 patients, 2 of which resulted in fracture. The average age of patients who fell was 63.9 (range 0 to 91) years. Many falls occurred at the bedside (68.2% %). Approximately half of all falls were related to elimination (46.6% %). The most common time of discovery of falls was 2 : 00-2 : 59 AM (14/154 ; 9.1% %), followed by early in the morning when patients would actively move. Fall rates in our hospital were 1.39 falls per 1,000 patient days. The department of respiratory medicine and rheumatology had the highest fall rate (3.08 falls per 1,000 patient days), followed by the departments of neurosurgery and neurology (2.98 falls per 1,000 patient days). This study revealed the characteristics of falls in an acute care hospital, and suggests that their notification in the hospital might help reduce the incidence of falls in hospitalized patients. J. Med. Invest. 65 : 81-84, February, 2018

show abstract

“…Some previous studies reported that falls often occurred in the patients' rooms (1,3,(13)(14)(19)(20). In our study, 79.2% of falls occurred in patients' rooms, and !…”

Section: Discussionsupporting

confidence: 49%

Falls among Hospitalized Patients in an Acute Care Hospital: Analyses of Incident Reports

et al. 2018

View full text Add to dashboard Cite

show abstract

“…In addition, six patients (46%) who were admitted for complications of BMT experienced continued strength loss after admission. Because weakness is a risk factor for falls, the degree of progressive weakness found in this study during the course of BMT might explain, in part, the finding by Ueki et al (2014) that patients undergoing allogeneic BMT had an increased risk of falling.…”

Section: Discussionmentioning

confidence: 68%

“…Patients undergoing BMT are at risk for falls. Ueki et al (2014) performed retrospective chart reviews on 77 patients who had received a BMT. The study found that 45% of the patients had sustained a fall while hospitalized, with about 70% of the falls occurring after engraftment, which was defined as more than three days of granulocyte counts of at least 5 x 10 8 /L.…”

Section: Background Weakness and Falls In Patients Undergoing Bone Mamentioning

confidence: 99%

Patterns of Hand Grip Strength and Detection of Strength Loss in Patients Undergoing Bone Marrow Transplantation: A Feasibility Study

Sayre¹,

Belza²,

Dorcy³

et al. 2017

ONF

View full text Add to dashboard Cite

show abstract

“…32 By contrast, the incidence of fall in allo-HCT patients has not been studied extensively, with a single small study reporting a 45% incidence rate. 35 We have identified several predictors of transplant-related delirium and fall, including falls within the last year, advanced age, PIM use, impaired functional status, thrombocytopenia, and decreased creatinine clearance. Previous studies in general medical and surgical patients have identified prior cognitive impairment, severity of illness, high-risk medications, visual impairment, and malnutrition as significant risk factors for delirium, 32,36 as well as age, female sex, decreased mobility, visual impairment, cognitive impairment, and the use of psychotropic medication as significant risk factors for mechanical fall.…”

Section: Discussionmentioning

confidence: 99%

Burden and impact of multifactorial geriatric syndromes in allogeneic hematopoietic cell transplantation for older adults

Lin¹,

Hilden

Elko³

et al. 2019

Blood Advances

View full text Add to dashboard Cite

Multifactorial geriatric syndromes are highly prevalent in older patients with cancer. Because an increasing number of older patients undergo allogeneic hematopoietic stem cell transplantation (allo-HCT), we examined the incidence and impact of transplant-related geriatric syndromes using our institutional database and electronic medical records. We identified 527 patients age 60 years or older who had undergone first allo-HCT from 2001 to 2016 for hematologic malignancies. From the initiation of conditioning to 100 days posttransplant, new geriatric syndromes were predominantly delirium with a cumulative incidence of 21% (95% confidence interval [CI], 18%-25%) at day 100 followed by fall at 7% (95% CI, 5%-9%). In multivariable analyses of available pretransplant variables, fall within the last year, potentially inappropriate use of medication, thrombocytopenia, and reduced creatinine clearance were significantly associated with delirium; age older than 70 years and impaired activities of daily living were significantly associated with fall. In the 100-day landmark analysis, both delirium (hazard ratio [HR], 1.66; 95% CI, 1.09-2.52; P = .023) and fall (HR, 2.14; 95% CI, 1.16-3.95; P = .026) were significantly associated with increased nonrelapse mortality; moreover, fall (HR, 1.93; 95% CI, 1.18-3.14; P = .016), but not delirium, was significantly associated with reduced overall survival. Here, we establish baseline incidences and risk factors of common transplant-related geriatric syndromes. Importantly, we demonstrate significant associations of delirium and fall with inferior transplant outcomes. The burden and impact of transplant-related geriatric syndromes warrant the institution of patient-centered, preemptive, longitudinal, and multidisciplinary interventions to improve outcomes for older allo-HCT patients.

show abstract

Risk Analysis of Falls in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Cited by 19 publications

References 14 publications

Falls among Hospitalized Patients in an Acute Care Hospital: Analyses of Incident Reports

Falls among Hospitalized Patients in an Acute Care Hospital: Analyses of Incident Reports

Patterns of Hand Grip Strength and Detection of Strength Loss in Patients Undergoing Bone Marrow Transplantation: A Feasibility Study

Burden and impact of multifactorial geriatric syndromes in allogeneic hematopoietic cell transplantation for older adults

Contact Info

Product

Resources

About