This study presents a detailed comparative analysis of different methods for evaluating seismic response in structures, focusing on maximum displacements and collapse assessment. The results obtained through modal spectral analysis, non-linear dynamic analysis, and the incremental pushover analysis applied to a specific structure are compared. It has been found that the choice of time step and the consideration of ductility are critical for obtaining accurate predictions. The results of the non-linear dynamic analysis of the building’s response indicate that an earthquake equivalent to the one that affected the city of Lorca (southeast Iberian Peninsula) in 2011 would have a devastating impact on the studied structure, highlighting the importance of the finite element method modelling in predicting the formation of plastic hinges and assessing structural safety. These findings highlight the importance of utilising multiple analysis approaches and detailed modelling to fully understand the seismic behaviour of structures and ensure adequate resistance and stability to extreme events.