Risk Factor of Preeclampsia in a Secondary Indonesian Hospital: A Case-Control Study

Kurniawati, Lady Aqnes; Aldika Akbar, Muhammad Ilham; Utomo, Budi; Aditiawarman,

doi:10.37506/ijfmt.v15i3.15839

Cited by 3 publications

(1 citation statement)

References 18 publications

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“…Women with a family history of hypertension were at 4.15 times more risk of developing pre-eclampsia than those without any family history. Similar results were found in studies conducted by Ganesh et al [8] showing an AOR of 5.48, Kurniawati et al [13] with an AOR of 3.37, and Machano et al [14] with an AOR of 6.45. These findings further strengthened our results of a nearly five times higher risk of pre-eclampsia in women with a family history of hypertension.…”

Section: Discussionsupporting

confidence: 89%

Risk Factors of Pre-eclampsia: A Hospital-Based Case-Control Study

Padhan¹,

Pradhan²,

Panda³

et al. 2023

Cureus

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IntroductionPre-eclampsia is a pregnancy-specific hypertensive disorder and is one of the leading causes of maternal and infant morbidity and mortality in India and worldwide. Evidence of the association between various risk factors and pre-eclampsia is scarce in developing countries. As pre-eclampsia remains a leading cause of maternal mortality and morbidity, focusing on the causes and risk factors of pre-eclampsia during antenatal surveillance would prevent maternal deaths and reduce the maternal mortality rate. Our study aimed to determine the risk factors of pre-eclampsia. Materials and methodsAn unmatched case-control study was conducted at Veer Surendra Sai Institute of Medical Sciences and Research (VIMSAR), Burla, Odisha, taking 100 cases of pre-eclampsia and 100 controls without preeclampsia from January 2021 to January 2023. The study population included patients admitted to the Obstetrics & Gynecology labor room. Study participants were selected randomly from the labor room thrice weekly. Data were collected using a predesigned pre-tested questionnaire and case report format. Data were analyzed using IBM SPSS Statistics for Windows, Version 26 (Released 2019; IBM Corp., Armonk, New York, United States). Appropriate statistical tests (Odds ratio, proportions, Chi-square test) were applied, and the final interpretation was made. ResultsFamily history of hypertension (AOR = 4.2), history of chronic hypertension (AOR = 13.7), and AB blood group (AOR = 3.6) were found to be significant risk factors for pre-eclampsia. No significant association was found between pre-eclampsia and factors such as mother's age, caste, mother's education, type of family, socioeconomic status, education and occupation of husband, family history of diabetes mellitus, parity, history of abortion, and anemia. ConclusionRisk factors identified in the present study can be used to identify women at risk of pre-eclampsia during antenatal check-ups to minimize the complications of pre-eclampsia in both the mother and the fetus.

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Section: Discussionsupporting

confidence: 89%

Risk Factors of Pre-eclampsia: A Hospital-Based Case-Control Study

Padhan¹,

Pradhan²,

Panda³

et al. 2023

Cureus

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Maternal Risk Factors and Birth Outcomes of Pregnancies Complicated by Preeclampsia: A Case–control Study in a Tertiary Care Hospital of Central India

Soni,

Tomar,

Gupta

et al. 2024

Journal of Primary Care Specialties

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Background: Preeclampsia contributes substantially to maternal and perinatal mortality. Reduction of maternal and perinatal mortality is a global priority, particularly in low- and middle-income countries like India. Preeclampsia is often overlooked during pregnancy and emerges as a significant contributor to mortality if not addressed proactively. Hence, the present study planned to explore maternal risk factors and birth outcomes in women with preeclampsia admitted for delivery in a tertiary care hospital. Materials and Methods: The present case–control study, including 100 matched cases and a similar number of controls, was carried out. For cases, pregnant women admitted for delivery, diagnosed with preeclampsia, while controls included all pregnant women admitted for delivery without preeclampsia were interviewed. A structured interview questionnaire, patient documents, and maternal and child protection (MCP) cards were used for data collection. Results: Family history of hypertension (odds ratio [OR] = 2.90, 95% confidence interval [CI] = 1.65–5.31), history of chronic hypertension (OR = 6.00, 95% CI = 1.97–18.27), and primiparity (OR = 1.28, 95% CI = 0.72–2.26) were significantly associated with preeclampsia. Preterm birth occurred in 58.1% of cases and 41.8% of controls. No associations were found between preeclampsia and the mode of delivery, gender, and birth weight of the baby. Conclusion: Women with a family history of hypertension, primiparous women, and those with a chronic history of hypertension have more tendency to adverse consequences of pregnancy and its outcomes like preterm births. Recognizing high-risk cases promptly and implementing effective management strategies are essential for planning and executing women’s health programs ultimately enhancing nationwide maternal and child health-care delivery.

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Evaluation of Serum Ferritin, Iron and C-Reactive Protein Level in Children with Febrile Seizure in Wasit Province, Iraq

Al-Janabi

2024

ejmhr

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Background: Febrile seizures are a commonplace pediatric neurological sickness, often related to fever and infections. Recent research suggest a capability hyperlink among iron deficiency, inflammation, and the prevalence of febrile seizures, but the relationship remains underexplored in particular populations. This study aimed to assess the affiliation between serum iron, ferritin levels, and inflammatory markers (C-reactive protein [CRP] and white blood cell [WBC] remember) in youngsters with febrile seizures in comparison to healthful controls.Methods: A case-manage study become performed involving a hundred youngsters aged 6 months to 6 years, with 50 kids who skilled febrile seizures (patient institution) and 40 age-matched healthful controls. Serum ferritin, iron, CRP degrees, and WBC counts had been measured and compared between the 2 groups. The data have been analyzed the usage of impartial t-assessments, Pearson correlation, and multivariate logistic regression.Results: Children within the febrile seizure institution had extensively decrease serum ferritin (40.5 ± 30.2 ng/mL) and iron levels (40.8 ± 15.3 μg/dL) as compared to controls (85.7 ± 20.4 ng/mL and 75.4 ± 18.7 μg/dL, respectively; p < 0.001). CRP ranges and WBC counts had been notably better within the affected person organization (25.6 ± 48 mg/L and 18,400 ± 5,200 cells/μL, respectively) compared to controls (2.3 ± 1.1 mg/L and 7,200 ± 1,800 cells/μL; p < 0.001). A robust bad correlation was observed among CRP ranges with each serum ferritin (r = -0.462) and serum iron (r = -0.625). Multivariate logistic regression identified lower serum iron and ferritin stages, and better CRP and WBC counts as good sized unbiased predictors of febrile seizures.Conclusion: The findings advise that iron deficiency and accelerated inflammatory markers are tremendous chance factors for febrile seizures in kids. These effects highlight the importance of monitoring iron repute and managing inflammation in pediatric sufferers prone to febrile seizures.

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Risk Factor of Preeclampsia in a Secondary Indonesian Hospital: A Case-Control Study

Cited by 3 publications

References 18 publications

Risk Factors of Pre-eclampsia: A Hospital-Based Case-Control Study

Risk Factors of Pre-eclampsia: A Hospital-Based Case-Control Study

Maternal Risk Factors and Birth Outcomes of Pregnancies Complicated by Preeclampsia: A Case–control Study in a Tertiary Care Hospital of Central India

Evaluation of Serum Ferritin, Iron and C-Reactive Protein Level in Children with Febrile Seizure in Wasit Province, Iraq

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