Risk factors and impact of nosocomial Acinetobacter baumannii bloodstream infections in the adult intensive care unit: a case–control study

Jang, Tsrang-Neng; Lee, S.-H.; Huang, Cheng-Hua; Lee, C.-L.; Chen, W.-Y.

doi:10.1016/j.jhin.2009.06.007

Cited by 96 publications

(87 citation statements)

References 24 publications

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“…Consistent with other studies, a longer hospital stay prior to infection, exposure to invasive procedures, and antibiotic use before infection and chronically ill patients were all significant predictors of Acinetobacter infection. 10,11,4 High rate of Acinetobacter spp. infection among patients with respiratory tract disorders may be explained in part by high levels of contamination on respirators and suctioning equipment, particularly in ICUs, which may lead to environmental reservoirs of resistant strains.…”

Section: Discussionmentioning

confidence: 99%

“…3 Very interestingly, their ubiquitous nature in the ICU environment and inadequate infection-control practice have continuously raised the incidence of Acinetobacter infections over the past two decades. 4 Acinetobacter is an opportunistic pathogen known for its intrinsic resistance to antibiotics and greater ability to rapidly acquire resistance genes as mobile genetic elements. Acinetobacter is considered to be the most common gram-negative organism colonized on the skin of hospital personnel, including ICU nurses and respiratory therapists.…”

Section: Introductionmentioning

confidence: 99%

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Risk Factors for Acinetobacter infections in the Intensive Care Unit at King Khalid Hospital- Najran, KSA

Aedh¹

2017

IOSR JDMS

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Risk Factors for Acinetobacter infections in the Intensive Care Unit at King Khalid Hospital- Najran, KSA

Aedh¹

2017

IOSR JDMS

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“…Acinetobacter enfeksiyonu için çalışmalarda belirlenen diğer temel risk faktörleri geniş spektrumlu antibiyotik kullanımı, öncesinde enfeksiyon, total parenteral beslenme ve invaziv prosedürlerin varlığı (periferik damar, arteryel ve santral venöz katater, mekanik ventilasyon, nazogastrik tüp, üriner katater) şeklinde belirtilmiştir (16)(17)(18)(19)(20) . Bizim de çalışmamızda saptadığımız risk faktörleri, öncesinde ve sonrasında kültürlerde üreme (Tablo 1), öncesinde antibiyotik kullanmı, idrar sondası, mekanik ventilasyon, nazogastrik sonda, total parenteral beslenme, santral venöz katater, transfüzyon öyküsü gibi invaziv prosedürler şeklinde saptandı.…”

Section: Discussionunclassified

Chracteristics of acinetobacter baumanii isolated patients with respiratory samples in intensive care unit

Özdemır¹,

Özdemir²

2016

Terh

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Results: During this period, Acinetobacter baumannii isolated in respiratory samples of 38 patients (female=16, male n=22). The mean age of the patients was 68.6±18.1 years, and mean duration of hospitalisation was 25.4±18.3 days. Acinetobacter baumannii could be isolated from the culture media of respiratory samples after an average of 13.4±9.4 days followin inoculation A total of 29 cases (76.3%) exited. The underlying diseases were evaluated, and most frequently hypertension, stroke, heart failure, diabetes and COPD were detected. Prior to antibiotic use, urinary catheter, mechanical ventilation, nasogastric tube, total parenteral nutrition, central venous catheter had been most frequently detected risk factors. APACHE 2 score of the patients at admission to the intensive care unit was 23.3±5.7. On culture antibiograms, highest susceptibility to colistin polymyxin, tobramycin, gentamicin, imipenem, ciprofloxacin was noted. Conclusion: As a result, in our intensive care unit high rates of mortality due to Acinetobacter baumanni were detected.

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“…It is an opportunistic pathogen known for its intrinsic resistance to antibiotics and greater ability to rapidly acquire resistance genes as mobile genetic elements (plasmids, transposons, integrons cassettes and insertion sequences). 6,1 In addition, their ubiquitous nature in the ICU environment coupled with inadequate infection-control practices have continuously raised the incidence of Acinetobacter infections over the past two decades. 7 The precise mechanisms that explain how multiple-drug resistance occurs are not fully known.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Acinetobacter infections among Intensive Care Unit's patients in Najran

Aedh¹

2017

Int. J. Curr. Res. Med. Sci.

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The rising prevalence of Acinetobacter infections in the intensive care units (ICUs) causes a great concern due their extraordinary ability to develop resistance to multiple classes of antimicrobial agents. This is a cross-sectional and facility based study that conducted in King Khalid hospital in Najran, Saudi Arabia. The aim of this study is to estimate the prevalence of Acinetobacter infections in the ICU patients, and to identify antibiotic susceptibility of the Acinetobacter isolates. 180 ICU patients were studied during the period from Aug. 2016 to April 2017. Acinetobacter was isolated in 21(11.7%) of patients. It was isolated from tracheal secretions in 43% of the isolates, followed by sputum (23%), wounds (14%), Central Venous Line (CVL) (9%), urine and blood (6%) for each respectively. Acinetobacter infection was increased significantly in patients with old ages, patients with chronic diseases and those undergoing invasive procedures (P=0.001). Acinetobacter sensitivity tests were performed, they showed that the isolates were resistant to many antibiotics in terms of Ampicillin, Cephalothin, Cefuroxime, Gentamycin, Amikacin, Tobramycin, Ofloxacine, Rifampicin and Colistin was respectively 87%, 86%, 79%, 76%, 52%, 43%, 33%, 32% and 8%. It was concluded that Acinetobacter is an important nosocomial infection pathogen in the ICU patients. Few treatment options are currently available, and for this reason, prevention and infection control measures are essential, including antibiotic control strategies in the ICUs.

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Risk factors and impact of nosocomial Acinetobacter baumannii bloodstream infections in the adult intensive care unit: a case–control study

Cited by 96 publications

References 24 publications

Risk Factors for Acinetobacter infections in the Intensive Care Unit at King Khalid Hospital- Najran, KSA

Risk Factors for Acinetobacter infections in the Intensive Care Unit at King Khalid Hospital- Najran, KSA

Chracteristics of acinetobacter baumanii isolated patients with respiratory samples in intensive care unit

Prevalence of Acinetobacter infections among Intensive Care Unit's patients in Najran

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