Risk Factors and Outcomes Associated With Sepsis After Coronary Artery Bypass and Open Heart Valve Surgeries

Karamnov, Sergey; Brovman, Ethan Y.; Greco, Katherine J.; Urman, Richard D.

doi:10.1177/1089253218785362

Cited by 8 publications

(7 citation statements)

References 65 publications

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“…In the current study, one patient was admitted to the infection service due to postoperative sepsis, and one female patient developed an abortion after vaginal bleeding. Sepsis was one of the complications observed after cardiac surgery (3). In a study, sepsis was reported in 1.9% (n=2) of the patients after valve surgery (n=23) (2).…”

Section: Discussionmentioning

confidence: 98%

“…Patients with mechanical heart valve surgery should be followed up in terms of the prosthetic valve and open heart surgery-related complications. In the long term, complications, such as heart failure, infective endocarditis, sternal wound infections, neurological complications, valve-related complications, acute renal failure, and sepsis can be observed due to open-heart surgery (2,3). Following these complications, problems, such as valve thrombosis, thromboembolism, and bleeding, may occur with mechanical prosthesis.…”

Section: Introductionmentioning

confidence: 99%

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Retrospective investigation of anticoagulant complications in long term after mechanical heart valve replacement surgery in Turkey

Kankaya

Bilik

Gencpinar

2020

ircmj

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Background: Patients with mechanical heart valve replacement surgery (MHVRS) should be followed up in terms of prosthetic valve-related and open heart surgery complications. This study aimed to determine the anticoagulant complications in long term in patients with MHVRS. Methods: This retrospective and descriptive study was conducted in a university hospital, İzmir, Turkey. The data were collected from July to December 2019. In total, 73 patients referring for regular check-ups to the hospital with intervals not exceeded more than 90 days, and those who had international normalized ratio (INR) measurements for January-April-July-October 2018 were included in this study. Results: The mean age of the patients was obtained at 58.98±12.89 years, and 53.4% (n=39) of the cases were male. Moreover, the mean follow-up period was estimated at 65.98±28.47 months. According to the results, complications developed in 60 patients (82.2%). The first hospitalized unit was the emergency department. The factors affecting the development of complications after MHVRS were evaluated, and a difference was found regarding gender (X2=6.18, P=0.013), comorbidities (X2=25.58, P=0.018), and monthly referral for regular check-ups to the hospital (X2=5.20, P=0.023). There was no relationship between the INR levels and the development of complications. Furthermore, the results of evaluating the factors affecting the number of hospitalizations after MHVRS revealed that monthly referral to hospital for check-ups (t=3.18, P=0.002) and history of previous valve surgery (Z=201.00, P=0.03) affected the number of hospitalizations. Conclusions: It was observed that patients frequently refer to the emergency department and struggled with various complications. Moreover, it was found that the patients had frequent bleeding and refer to the emergency service repeatedly. Accordingly, there is a need for interventional studies to reduce postoperative complications and provide the therapeutic INR level.

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Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Retrospective investigation of anticoagulant complications in long term after mechanical heart valve replacement surgery in Turkey

Kankaya

Bilik

Gencpinar

2020

ircmj

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“…Снижение уровня альбумина в большей степени свидетельствует о системном воспалении и мало зависит от нутритивного статуса, как принято полагать [42]. Так, по данным разных авторов, уровни альбумина при сепсисе [43][44][45] и ВГФС [46][47][48] сходны, при этом во всех работах отмечено ухудшение прогноза у пациентов с гипоальбуминемией. С-реактивный белок и прокальцитонин являются маркерами как воспаления в целом, так и бактериальной инфекции в частности [49,50].…”

Section: рис 3 корреляционный анализ концентрации общего и гликозилunclassified

Clinical and Laboratory Characteristics and Differential Diagnosis between Secondary Hemophagocytic Syndrome and Sepsis

Потапенко¹,

Первакова²,

Титов³

et al. 2019

Клиническая онкогематология

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Актуальность. Вторичный гемофагоцитарный синдром (ВГФС) и сепсис при всей схожести клинических проявлений и лабораторных параметров принципиально различаются по применяемым при этих заболеваниях методам лечения. При ВГФС лечение направлено на достижение иммуносупрессии, а при сепсисе проводится противоинфекционная терапия. Для выбора правильной лечебной тактики необходима быстрая дифференциальная диагностика между заболеваниями. Цель. Поиск и анализ критериев дифференциальной диагностики ВГФС и сепсиса. Материалы и методы. Проанализированы данные 102 пациентов: 55-с ВГФС (медиана возраста 60 лет, диапазон 18-81 год) и 47-с сепсисом (медиана возраста 60 лет, диапазон 18-89 лет). Диагноз ВГФС установлен на основании критериев HLH-2004 и H-Score. Сепсис верифицирован при документированном очаге

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“…In fact, high APACHE II, SAPS and SOFA scores, acute kidney injury and sepsis in the early postoperative period, which can actually lead to an increased fluid balance, have been associated independently with increased risk of early deaths after cardiac surgery. [6][7][8] In our opinion, no matter how refined the adjustment is for differences in early postoperative conditions, it is never possible to ensure a complete adjustment for differences between non-survivors and survivors. Furthermore, postoperative fluid balance has been significantly associated with increased risk of acute kidney injury after cardiac surgery.…”

Section: Sirmentioning

confidence: 99%

Assessing association of early fluid balance with mortality after cardiovascular surgery

et al. 2019

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Risk Factors and Outcomes Associated With Sepsis After Coronary Artery Bypass and Open Heart Valve Surgeries

Cited by 8 publications

References 65 publications

Retrospective investigation of anticoagulant complications in long term after mechanical heart valve replacement surgery in Turkey

Retrospective investigation of anticoagulant complications in long term after mechanical heart valve replacement surgery in Turkey

Clinical and Laboratory Characteristics and Differential Diagnosis between Secondary Hemophagocytic Syndrome and Sepsis

Assessing association of early fluid balance with mortality after cardiovascular surgery

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