Risk Factors for Acinetobacter Baumannii (Ab) Nosocomial Bacteremia in Critically Ill Patients

Garcia-Garmendia, JL; Gamacho-Montero, J; Ortíz-Leyba, Carlos; Jiménez-Jiménez, F J; Gili-Miner, M.

doi:10.1097/00003246-199901001-00348

Cited by 62 publications

(86 citation statements)

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“…Non-random sampling method was adopted for the study. The following variables were analyzed: ICU admission, duration of stay in the hospital, mechanical ventilation, endotracheal intubation, the presence of underlying diseases or conditions, including chronic obstructive pulmonary disease (COPD), diabetes mellitus, hypertension, chronic kidney disease (CKD), chronic liver disease, ischemic heart disease, malignancy, past history of device implantation or surgery, and instrumentation at various sites such as Central venous catheters [4][5][6][7]. Ventilator-associated pneumonia (VAP) is defined according to the American Thoracic Society as pneumonia that occurs 48-72 hrs or thereafter following endotracheal intubation, characterized by the presence of a new or progressive infiltrate, signs of systemic infection (fever, altered white blood cell count), changes in sputum characteristics, and detection of a causative agent [8].…”

Section: Methodsmentioning

confidence: 99%

A Rising Threat – Risk Factors and Outcomes Related to Infections With Acinetobacter Species

Khurana¹,

Baliga

Shenoy

et al. 2017

Asian J Pharm Clin Res

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Objective: Acinetobacter species is an important cause of community as well as nosocomial infections with a high mortality rate. The study was done to analyze the risk factors associated with Acinetobacter infections and their outcomes. Methods:The clinical details of 100 patients having infections with Acinetobacter species over a period of 1-year were analyzed for underlying risk factors and outcomes. The antibiotic sensitivity results were interpreted according to the Clinical Laboratory Standards Institute guidelines.Results: Majority of the infections caused by the Acinetobacter species were lower respiratory tract infections, most common being ventilatorassociated pneumonia. 47% of the isolates were multi drug resistant and 26% were extensively drug resistant. There is a significant chance of drug resistance and a poor outcome with intensive care unit (ICU) stay, prolonged hospital stay of more than 7 days, the presence of 5 or more risk factors. Endotracheal intubation and mechanical ventilation were the risk factors for increased drug resistance in the ICU. Drug resistance was also seen more frequently in patients with chronic obstructive pulmonary disease, chronic kidney disease, and patients on post-operative care. Conclusion:The steady increase in drug resistant Acinetobacter species and limited antibiotics available advocates an uncompromising approach toward infection control and a judicious use of antibiotics especially in the ICU. An understanding about the risk factors helps in the appropriate approach and management of the patient.

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Section: Methodsmentioning

confidence: 99%

A Rising Threat – Risk Factors and Outcomes Related to Infections With Acinetobacter Species

Khurana¹,

Baliga

Shenoy

et al. 2017

Asian J Pharm Clin Res

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show abstract

“…Measures described in the clinical trials include hand disinfection by using either alcohol hand-gel or Chlorhexidine. 23 Barrier and contact precautions such as wearing gloves, gowns, and masks are so essential. Additionally, restricted use of third generation cephalosporins along with other antibiotics control strategy could be useful.…”

Section: Acinetobactermentioning

confidence: 99%

Prevalence of Acinetobacter infections among Intensive Care Unit's patients in Najran

Aedh¹

2017

Int. J. Curr. Res. Med. Sci.

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The rising prevalence of Acinetobacter infections in the intensive care units (ICUs) causes a great concern due their extraordinary ability to develop resistance to multiple classes of antimicrobial agents. This is a cross-sectional and facility based study that conducted in King Khalid hospital in Najran, Saudi Arabia. The aim of this study is to estimate the prevalence of Acinetobacter infections in the ICU patients, and to identify antibiotic susceptibility of the Acinetobacter isolates. 180 ICU patients were studied during the period from Aug. 2016 to April 2017. Acinetobacter was isolated in 21(11.7%) of patients. It was isolated from tracheal secretions in 43% of the isolates, followed by sputum (23%), wounds (14%), Central Venous Line (CVL) (9%), urine and blood (6%) for each respectively. Acinetobacter infection was increased significantly in patients with old ages, patients with chronic diseases and those undergoing invasive procedures (P=0.001). Acinetobacter sensitivity tests were performed, they showed that the isolates were resistant to many antibiotics in terms of Ampicillin, Cephalothin, Cefuroxime, Gentamycin, Amikacin, Tobramycin, Ofloxacine, Rifampicin and Colistin was respectively 87%, 86%, 79%, 76%, 52%, 43%, 33%, 32% and 8%. It was concluded that Acinetobacter is an important nosocomial infection pathogen in the ICU patients. Few treatment options are currently available, and for this reason, prevention and infection control measures are essential, including antibiotic control strategies in the ICUs.

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“…Variety and coexistence of resistance mechanisms in this bacterium consequence in multiple drug resistance and can create troubles in treatment [9,[11][12][13]. Immunosuppressed patients, patients with severe inherent diseases, and those gone through invasive processes and subjected to broad-spectrum antibiotics are vulnerable to MDRAB infections [14]. Completely working antibiotic choices available to treat hospitalacquired infections with MDRAB are critically limited [15].…”

Section: Introductionmentioning

confidence: 99%

Isolation and Identification of Multi-Drug Resistant Acinetobacter baumannii from a tertiary health care centre of Bangladesh

Dhar¹,

Mahmud²,

Chowdhury³

et al. 2017

IOSRJPBS

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Risk Factors for Acinetobacter Baumannii (Ab) Nosocomial Bacteremia in Critically Ill Patients

Cited by 62 publications

References 0 publications

A Rising Threat – Risk Factors and Outcomes Related to Infections With Acinetobacter Species

A Rising Threat – Risk Factors and Outcomes Related to Infections With Acinetobacter Species

Prevalence of Acinetobacter infections among Intensive Care Unit's patients in Najran

Isolation and Identification of Multi-Drug Resistant Acinetobacter baumannii from a tertiary health care centre of Bangladesh

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