Risk factors for benign paroxysmal positional vertigo recurrence: a systematic review and meta-analysis

Chen, Jinbao; Zhang, Senlin; Cui, Kai; Liu, Chuxuan

doi:10.1007/s00415-020-10175-0

Cited by 63 publications

(67 citation statements)

References 52 publications

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“…The cause of BPPV is mostly unknown although cases may be associated with head trauma, a prolonged recumbent position, or various disorders involving the inner ear [16]. Other risk factors for BPPV may include female gender, age under 65 years, a high income, living in a metropolis, osteoporosis, hypertension, and non-apnea sleep disorders [17][18][19][20]. Indeed, a recent meta-analysis found that female gender, hypertension, diabetes mellitus, hyperlipidemia, osteoporosis, and vitamin D deficiency are risk factors for recurrences of BPPV [19].…”

Section: Pathophysiologymentioning

confidence: 99%

“…Other risk factors for BPPV may include female gender, age under 65 years, a high income, living in a metropolis, osteoporosis, hypertension, and non-apnea sleep disorders [17][18][19][20]. Indeed, a recent meta-analysis found that female gender, hypertension, diabetes mellitus, hyperlipidemia, osteoporosis, and vitamin D deficiency are risk factors for recurrences of BPPV [19]. Linked to this is the finding that elderly women with a lack of physical activity have a 2.6 times higher risk for BPPV than those who undertake regular activity [21].…”

Section: Pathophysiologymentioning

confidence: 99%

“…Otolin-1 is an inner ear-specific collagen that forms a scaffold to promote optimal formation of the otoconia. Owing to its potential passage through the labyrinth-blood barrier, otolin-1 can be detected in the peripheral blood and may serve a biomarker for BPPV [19]. Thus, high serum levels of otolin-1 (> 300 pg/ml) may discriminate patients with BPPV from healthy controls [20].…”

Section: Diagnosismentioning

confidence: 99%

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Update on benign paroxysmal positional vertigo

2020

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Benign paroxysmal positional vertigo (BPPV) is the most common cause of vertigo worldwide. This review considers recent advances in the diagnosis and management of BPPV including the use of web-based technology and artificial intelligence as well as the evidence supporting the use of vitamin D supplements for patients with BPPV and subnormal serum vitamin D. Keywords Dizziness • Vertigo • Benign paroxysmal positional vertigo Hyo-Jung Kim and JaeHan Park equally contributed to this study.

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Section: Pathophysiologymentioning

confidence: 99%

Section: Pathophysiologymentioning

confidence: 99%

Section: Diagnosismentioning

confidence: 99%

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Update on benign paroxysmal positional vertigo

2020

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“…Bilateral bipolar square wave direct current GVS may induce slight pain at the site of electrode placement after stimulation with 1.5 mA intensity in healthy and stroke patients ( Utz et al, 2011 ; Dlugaiczyk et al, 2019 ). Further, GVS may induce a sensation of vertigo/dizziness ( Dlugaiczyk et al, 2019 ) and nausea ( Quinn et al, 2015 ), and these sensations might appear in a patient with a vestibular disorder ( Chen et al, 2020 ). Therefore, data on the degree of pain, vertigo/dizziness, and uncomfortable feeling were collected from all participants after examination using the nGVS montage.…”

Section: Introductionmentioning

confidence: 99%

No Impact of Stochastic Galvanic Vestibular Stimulation on Arterial Pressure and Heart Rate Variability in the Elderly Population

Matsugi

Nagino

Shiozaki

et al. 2021

Front. Hum. Neurosci.

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ObjectiveNoisy galvanic vestibular stimulation (nGVS) is often used to improve postural stability in disorders, such as neurorehabilitation montage. For the safe use of nGVS, we investigated whether arterial pressure (AP) and heart rate vary during static supine and slow whole-body tilt with random nGVS (0.4 mA, 0.1–640 Hz, gaussian distribution) in a healthy elderly population.MethodsThis study was conducted with a double-blind, sham-controlled, cross-over design. Seventeen healthy older adults were recruited. They were asked to maintain a static supine position on a bed for 10 min, and the bed was tilted up (TU) to 70 degrees within 30 s. After maintaining this position for 3 min, the bed was passively tilted down (TD) within 30 s. Real-nGVS or sham-nGVS was applied from 4 to 15 min. The time course of mean arterial pressure (MAP) and RR interval variability (RRIV) were analyzed to estimate the autonomic nervous activity.ResultnGVS and/or time, including pre-/post-event (nGVS-start, TU, and TD), had no impact on MAP and RRIV-related parameters. Further, there was no evidence supporting the argument that nGVS induces pain, vertigo/dizziness, and uncomfortable feeling.ConclusionnGVS may not affect the AP and RRIV during static position and whole-body tilting or cause pain, vertigo/dizziness, and discomfort in the elderly.

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“…Furthermore, several studies reported the association of BPPV with inner ear diseases including vestibular neuritis, Menière's disease as well as vascular risk factors (e.g., hypertension, diabetes mellitus) [7]. Previous studies on the recurrence and long-term prognosis of BPPV conducted by domestic and international investigators have shown that similar factors that increase the risk of BPPV might be associated with the recurrence of BPPV as well [8][9][10][11][12]. However, the results were considerably inconsistent among studies and still need to be elucidated.…”

Section: Introductionmentioning

confidence: 99%

Clinical Characteristics of Recurrent Benign Paroxysmal Positional Vertigo: A Retrospective Cohort Study

Kim¹,

Cho²,

Lee³

et al. 2021

Res Vestib Sci

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Objectives: Benign paroxysmal positional vertigo (BPPV) is a potentially recurrent disease even after successful canalith repositioning maneuvers. However, the exact recurrence rate or any clinical factors affecting the recurrence of BPPV still need to be elucidated. Methods: We recruited patients diagnosed as BPPV in a tertiary hospital for 3 years. We retrospectively reviewed the clinical information of the patients including baseline demographics, comorbidities and predisposing factors through the electronic medical records. We performed a telephone survey or direct interview 3 to 6 years later from the initial diagnosis of BPPV was made. To determine the factors associated with the recurrence, we divided study population into two subgroups; 'recurrence group' vs. 'recurrence-free group.' Then, intergroup comparative analyses were performed. Results: Among 397 patients who were originally eligible for the study, we performed a telephone survey or direct interview in 289 patients (72.8%) to determine the recurrence of BPPV. The overall recurrence rate was 29.4% (85 of 289). Baseline demographics except female gender (p=0.014) were not different between subgroups. Neither clinical characteristics nor vascular comorbidities were associated with the recurrence. However, patients with low bone mineral density (BMD; T-score below -1, osteopenia/osteoporosis) showed significantly higher recurrence than those with normal BMD (40.6% vs. 0%, p=0.009). Conclusions: Female gender and low BMD (T-score below -1) were associated with the recurrence of BPPV in this study. Further researches in various clinical settings with larger sample size are warranted to identify the factors affecting the relapse of BPPV.

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Risk factors for benign paroxysmal positional vertigo recurrence: a systematic review and meta-analysis

Cited by 63 publications

References 52 publications

Update on benign paroxysmal positional vertigo

Update on benign paroxysmal positional vertigo

No Impact of Stochastic Galvanic Vestibular Stimulation on Arterial Pressure and Heart Rate Variability in the Elderly Population

Clinical Characteristics of Recurrent Benign Paroxysmal Positional Vertigo: A Retrospective Cohort Study

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