Risk Factors for Development of Rhegmatogenous Retinal Detachment in Patients with Uveitis

Abstract

Prevalence of RRD in uveitis was 7% and development of RRD was encountered in posterior and panuveitis. Infectious uveitis (specifically ARN) formed a high risk for RRD.

Postoperative Posterior Segment Complications After Boston Type 1 Keratoprosthesis

“…Although other investigators have reported that cicatrizing conjunctivitis is associated with an increased risk of RD after KPro implantation, we did not find such an association. 24–26 Similar to a report by Chak et al, we did not find an association between the performance of a YAG laser membranotomy for a RPM and an increased risk of RD, as reported by Jardeleza et al 24,27 However, our findings that postoperative aphakia and idiopathic vitritis were associated with an increased risk of RD are consistent with those of Jardeleza et al 24…”

“…Although other investigators have reported that cicatrizing conjunctivitis is associated with an increased risk of RD after KPro implantation, we did not find such an association. [24][25][26] Similar to a report by Chak et al, we did not find an association between the performance of a YAG laser membranotomy for a RPM and an increased risk of RD, as reported by Jardeleza et al 24,27 However, our findings that postoperative aphakia and idiopathic vitritis were associated with an increased risk of RD are consistent with those of Jardeleza et al Our center has previously reported on the safety of concurrent KPro and tube shunt implantation and demonstrated that the incidence of sight-threatening postoperative complications was not increased in eyes in which a tube shunt was implanted with the KPro compared with eyes in which a tube shunt was not. 6 Although our prior study was not sufficiently powered to detect differences between these two groups for each postoperative complication, the 6.5% of eyes that developed a RD in the group that underwent concurrent KPro and tube shunt implantation was approximately half of the 12.1% that developed a RD in the group in which a tube was not implanted.…”

“…Vitritis was also identified as a risk factor for RD, which was predictable, as vitreous inflammation increases the likelihood of a retinal break, and thus a RD, by enhancing posterior vitreous detachment and morphological changes of the vitreous base. 24,27 We have recently reported that the development of infectious keratitis significantly increases the risk of developing idiopathic vitritis, suggesting that what has traditionally been referred to as sterile vitritis may in fact have an infectious etiology. 4,12,16 Given this, in addition to the fact that the clinical differentiation of idiopathic vitritis from endophthalmitis may be difficult, we recommend that a vitreous tap and injection be considered in all cases of more than mild vitritis, even when a corneal infiltrate is not observed.…”

Retinal Detachment in Eyes With Boston Type 1 Keratoprosthesis

“…21 Vitreous inflammation can lead to posterior vitreous detachment with subsequent retinal breaks, and idiopathic vitritis is a reported risk factor for RD after KPro. 4,21,22 Idiopathic vitritis occurred frequently in our series, but detailed risk factor analysis was not performed because of the small cohort size and is reported elsewhere. 4 It has also been shown that a chronic low grade of inflammation from the KPro device itself can promote a strong inflammatory response within the retina, leading to an aggressive PVR response following RD.…”

Retinal Detachment Associated With Acute Retinal Necrosis

“…ARN has the highest rate of RRD of any uveitis. 17 The reported rate of RRD in ARN varies widely from 20% to 73%. 4,6,[8][9][10][18][19][20][21][22][23][24][25] This wide range likely results from differences in ARN severity, time to treatment, treatment plan, and length of follow-up.…”