Risk factors for early degeneration of allografts in pulmonary circulation

Schorn, K.; Yankah, A. C.; Alexi-Meskhishvili, V.; Weng, Yuguo; Lange, Peter; Hetzer, Roland

doi:10.1016/s1010-7940(96)01003-2

Cited by 32 publications

(21 citation statements)

References 34 publications

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“…Late death and dysfunction of the pulmonary homograft were assessed with more emphasis [2,3,[5][6][7][10][11][12]. In our study, hospital mortality was 18%, in accordance with the literature, on which mortality ranges from 6% to 27% [2.5-10].…”

Section: Discussionsupporting

confidence: 82%

“…Few studies have focused on hospital mortality for surgical repair of the obstructive diseases of the right heart, citing only its rate, but rather than assessing the risk factors [5][6][7][8][9][10]. Late death and dysfunction of the pulmonary homograft were assessed with more emphasis [2,3,[5][6][7][10][11][12].…”

Section: Discussionmentioning

confidence: 99%

“…The small size of the pulmonary homograft and the diagnosis of truncus arteriosus are involved in studies by Razzouk et al [12] and Schorn et al [10].…”

Section: Discussionmentioning

confidence: 99%

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Mortalidade hospitalar na cirurgia de reconstrução da via de saída do ventrículo direito com homeonxerto pulmonar

Lenzi

Miyague²,

Ferreira

et al. 2010

Rev Bras Cir Cardiovasc

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Mortalidade hospitalar na cirurgia de reconstrução da via de saída do ventrículo direito com homeonxerto pulmonarHospital mortality in surgery for right ventricular outflow tract reconstruction using pulmonary homograft Abstract Background: Hospital mortality in surgical reconstruction of the right ventricular outflow tract using pulmonary homograft is variable.Objectives: To identify risk factors associated with hospital mortality and patients' clinical profile.Methods: Study on children who had undergone reconstruction of the right ventricular outflow tract using pulmonary homograft. We analyzed as risk factors the clinical and surgical variables and prosthesis's morphological aspects.Results: Ninety-two patients underwent surgery between 1998 and 2005, presenting mainly pulmonary atresia with ventricular septal defect and tetralogy of Fallot. Forty patients were treated in the first month of life. 38 patients needed Blalock Taussig surgeries due to clinical severity. The median age at surgery for total correction was 22 months, ranging from 1 to 157 months. Pulmonary homograft size ranged from 12 to 26 mm and length of cardiopulmonary bypass was 132 ± 37 minutes. Postoperatively, there were seventeen deaths (18% cases), on average 10.5 ± 7.5 days after surgery. The predominant cause was multiple organ failure. In the univariate analysis between the types of heart disease, they related to age, time of surgery, size of homograft, pulmonary valve Z value, CPB time, maintenance of the integrity of the homograft and pulmonary tree change. There was no statistical difference in hospital mortality between the variables and the type of heart disease.Conclusion: The right-sided obstructive heart diseases require surgical care in the first days of life. The total correction surgery has a mortality risk rate of 18% but there was no association with any variable studied.Descriptors: Heart defects, congenital. Cardiovascular surgical procedures. Transplantation, homologous. Mortality. Resumo

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Section: Discussionsupporting

confidence: 82%

Section: Discussionmentioning

confidence: 99%

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Mortalidade hospitalar na cirurgia de reconstrução da via de saída do ventrículo direito com homeonxerto pulmonar

Lenzi

Miyague²,

Ferreira

et al. 2010

Rev Bras Cir Cardiovasc

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“…Although some studies have found no difference in efficacy between the aortic and pulmonary homograft, 21,25 most have supported the superiority of the latter. [22][23][24] Accordingly, we preferentially used pulmonary homografts in the present series. As a result, because there were so few patients with aortic homograft implantation, the present study does not resolve the issue of which homograft type is preferable.…”

Section: Discussionmentioning

confidence: 99%

Right Ventricle to Pulmonary Artery Reconstruction Using a Valved Homograft

Tatebe

Nagakura

Boyle

et al. 2003

Circ J

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“…All kinds of conduits have some disadvantages such as degeneration or lack of growth potential through time. [5] Contegra results vary in reports, although long-term complication is usually conduit stenosis which is mostly seen in smaller diameter conduits. [6,7] Dilatation of the Contegra conduit is rare.…”

mentioning

confidence: 99%

Outcomes of truncus arteriosus repair with bovine jugular vein conduit

Erek

Temur

Suzan

et al. 2018

Turk Gogus Kalp Dama

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ÖZAmaç: Bu çalışmada Rastelli tipi trunkus arteriyozus olan hastalarda trunkus arteriyozus tamirinin sonuçları değerlendirildi.Çalışma planı: Ocak 2011 -Mart 2017 tarihleri arasında 13 hastaya (7 erkek, 6 kadın; medyan yaş 37 gün; dağılım, 16-60 gün) Contegra kondüiti kullanılarak trunkus arteriyozus tamiri yapıldı. Ameliyat öncesi tanı sekiz hastada trunkus arteriyozus tip 1 (Edwards-Collett), üç hastada tip 2, bir hastada tip 3 ve bir hastada tip 4 idi. Ameliyat için kullanılan Contegra kondüitleri 14 mm (n=5), 12 mm (n=7) ve 16 mm (n=1) idi. Bul gu lar:İki hastada (%15.4) erken ölüm görüldü. Medyan yoğun bakım ve hastanede kalış süreleri sırasıyla 10 (dağılım 6-14) ve 20 (dağılım 14-41) gün idi. Medyan takip süresi 36 (dağılım, 2-66) ay idi. Dört hastada (%31) takip sırasında kondüit boyutları ciddi şekilde artış gösterdi ve iki hastada 23 mm'ye, bir hastada 20 mm'ye ve diğer hastada 18 mm'ye ulaştı. Üç hastada orta derecede distal kondüit darlığı vardı. Dört hastada orta derecede pulmoner yetmezlik ve bir hastada ciddi pulmoner yetmezlik vardı. İki hastada orta derecede trunkal kapak yetmezliği ve bir hastada orta derecede rezidüel ventriküler septal defekt vardı. Hastaların hiçbirinde tekrar ameliyat gereksinimi olmadı.Sonuç: Contegra kondüiti bebeklerde trunkus arteriyozus tamiri için iyi bir alternatiftir; ancak, distal kondüit darlığı ve kondüit dilatasyonu gelişebileceği için yakın izlem gereklidir. ABSTRACT Background:In this study, we aimed to evaluate the outcomes of truncus arteriosus repair in patients undergoing Rastelli type truncus arteriosus.

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Risk factors for early degeneration of allografts in pulmonary circulation

Abstract: The use of pulmonary allografts, avoidance of relatively short and small conduits of < 14 mm in diameter, might improve the durability of allografts in infants and small children.

Cited by 32 publications

References 34 publications

Mortalidade hospitalar na cirurgia de reconstrução da via de saída do ventrículo direito com homeonxerto pulmonar

Mortalidade hospitalar na cirurgia de reconstrução da via de saída do ventrículo direito com homeonxerto pulmonar

Right Ventricle to Pulmonary Artery Reconstruction Using a Valved Homograft

Outcomes of truncus arteriosus repair with bovine jugular vein conduit

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