1982
DOI: 10.1001/archderm.1982.01650230028021
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Risk Factors for Local Recurrence of Primary Cutaneous Squamous Cell Carcinomas

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Cited by 70 publications
(23 citation statements)
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“…Griffiths et al estimated BCC recurrence rates after conventional surgical excision to be between 1.3% and 2% over a minimum of 5 years follow up 44 . For primary SCCs, reported 5‐year recurrence rates range from 3% to 8% 45–47 for completely excised tumors and are unknown for incompletely excised SCC. For SCC in situ , reported 5‐year recurrence rates range from 6.3% after Mohs surgery 48 to 5–19% after surgical excision 49,50 …”
Section: Discussionmentioning
confidence: 99%
“…Griffiths et al estimated BCC recurrence rates after conventional surgical excision to be between 1.3% and 2% over a minimum of 5 years follow up 44 . For primary SCCs, reported 5‐year recurrence rates range from 3% to 8% 45–47 for completely excised tumors and are unknown for incompletely excised SCC. For SCC in situ , reported 5‐year recurrence rates range from 6.3% after Mohs surgery 48 to 5–19% after surgical excision 49,50 …”
Section: Discussionmentioning
confidence: 99%
“…52 Since about 90 percent of recurrences and metastases occur during the first five years after treatment, screening during this period may be adequate. [53][54][55] Organ-transplant recipients should undergo regular screening examinations regardless of whether they have any history of skin cancer. 56 According to commonly accepted guidelines, patients who have a history of nonmelanoma skin cancer or who have predisposing conditions should undergo screening once or twice yearly.…”
Section: Screening and Detectionmentioning
confidence: 99%
“…We did not do a pooled analysis of other features considered to confer high risk owing to different reporting methods in the studies in which these factors were considered. Increased risk of recurrence with tumours > 2 cm was noted in some of the included studies, 544,551,573 although this finding was not supported by Mourouzis et al, 553 with 60% of metastases originating in SCCs < 2 cm, nor by Dzubow et al, 570 who found a trend towards significance with tumours > 5 cm in diameter. Several studies showed the importance of SCC depth as a risk factor for recurrence.…”
Section: Stratification Of Riskmentioning
confidence: 80%
“…545,558,[564][565][566][567][568][569][570][571][572][573][574][575][576][577] In a seminal series of papers, Mohs reported 5-year cure rates for previously untreated SCCs of 95.7% for SCC of the trunk and extremities; 578 96.6% for the ear; 579 97.8% for facial, scalp and neck SCCs; 578 98.5% for eyelid SCCs; 580 and 98.8% for SCCs of the nose. 578 These rates translated to a pooled 5-year cure rate 97.4% for the 2133 SCCs at all sites (95% CI 96.2% to 98.3%; I 2 = 48%).…”
Section: Mohs Micrographic Surgerymentioning
confidence: 99%