Risk Factors for Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA) Acquisition in Roommate Contacts of Patients Colonized or Infected With MRSA in an Acute-Care Hospital

Moore, Christine; Dhaliwal, Jastej; Tong, Agnes; Eden, Sarah; Wigston, Cindi; Willey, Barbara M.; McGeer, Allison

doi:10.1086/588567

Cited by 55 publications

(31 citation statements)

References 37 publications

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“…Similarly, we showed that covered wounds or skin lesions protect significantly against transmission of MRSA from index persons to their household contacts. This is contrary to the results of a study by Moore et al showing that broken skin or chronic skin lesions contribute to the acquisition of MRSA in roommate contacts with MRSA colonization or infection (25). We assume that in our setting, due to strict aseptic wound care, including proper coverage of wounds and hygienic precautions, the risk of MRSA transmission may be significantly lowered.…”

Section: Discussioncontrasting

confidence: 77%

Transmission of Methicillin-Resistant Staphylococcus aureus to Household Contacts

et al. 2010

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The frequency of and risk factors for methicillin-resistant Staphylococcus aureus (MRSA) transmission from a MRSA index person to household contacts were assessed in this prospective study. Between January 2005 and December 2007, 62 newly diagnosed MRSA index persons (46 patients and 16 health care workers) and their 160 household contacts were included in the study analysis. Transmission of MRSA from an index person to household contacts occurred in nearly half of the cases (47%; n ‫؍‬ 29). These 29 index persons together had 84 household contacts, of which two-thirds (67%; n ‫؍‬ 56) became MRSA positive. Prolonged exposure time to MRSA at home was a significant risk factor for MRSA transmission to household contacts. In addition, MRSA colonization at least in the throat, younger age, and eczema in index persons were significantly associated with MRSA transmission; the presence of wounds was negatively associated with MRSA transmission. Furthermore, an increased number of household contacts and being the partner of a MRSA index person were householdrelated risk factors for MRSA acquisition from the index person. No predominant pulsed-field gel electrophoresis (PFGE) type was observed to be transmitted more frequently than other PFGE types. To date, screening household contacts and providing MRSA eradication therapy to those found positive simultaneously with the index person is not included in the "search-and-destroy" policy. We suggest including both in MRSA prevention guidelines, as this may reduce further spread of MRSA.

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Section: Discussioncontrasting

confidence: 77%

Transmission of Methicillin-Resistant Staphylococcus aureus to Household Contacts

et al. 2010

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“…Die Übertragungswahrscheinlich-keit korreliert mit Faktoren, die die Freisetzung bzw. Einwirkung beeinflussen, dem Kolonisationsdruck (d. h. dem Verhältnis von kolonisierten zu nicht kolonisierten Personen) [189], der Erregerdichte [190], dem Übertragungsweg [186,191] und dem Übertragungsziel [40, 186] sowie der Vorerkrankung des Empfängers [40,192].…”

Section: Definitionen/glossarunclassified

Empfehlungen zur Prävention und Kontrolle von Methicillin-resistenten Staphylococcus aureus-Stämmen (MRSA) in medizinischen und pflegerischen Einrichtungen

Ruscher

2014

Bundesgesundheitsbl.

126

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“…[2][3][4][5][6][7][8] Undetected MRSA-positive patients serve as reservoirs, and roommates of such patients and health care personnel are at significant risk of becoming colonized. [9][10][11][12][13] In addition, MRSA-positive persons contaminate the hospital's environment turning it into a reservoir for other patients. [14][15][16][17] After discharge from hospital, MRSA-positive patients may transmit their strain to their household members.…”

Section: Introductionmentioning

confidence: 99%

Epidemiology of Staphylococcus aureus Harboring the mecA or Panton-Valentine Leukocidin Genes in Hospitals in Java and Bali, Indonesia

Santosaningsih

Santoso

Budayanti

et al. 2014

The American Society of Tropical Medicine and Hygiene

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Abstract. Data of Staphylococcus aureus carriage in Indonesian hospitals are scarce. Therefore, the epidemiology of S. aureus among surgery patients in three academic hospitals in Indonesia was studied. In total, 366 of 1,502 (24.4%) patients carried S. aureus. The methicillin-resistant S. aureus (MRSA) carriage rate was 4.3%, whereas 1.5% of the patients carried Panton-Valentine leukocidin (PVL)-positive methicillin-sensitive S. aureus (MSSA). Semarang and Malang city (odds ratio [OR] 9.4 and OR 9.0), being male (OR 2.4), hospitalization for more than 5 days (OR 11.708), and antibiotic therapy during hospitalization (OR 2.6) were independent determinants for MRSA carriage, whereas prior hospitalization (OR 2.5) was the only one risk factor for PVL-positive MSSA carriage. Typing of MRSA strains by Raman spectroscopy showed three large clusters assigned type 21, 24, and 38, all corresponding to ST239-MRSA-SCCmec type III. In conclusion, MRSA and PVL-positive MSSA are present among patients in surgical wards in Indonesian academic hospitals.

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Risk Factors for Methicillin-Resistant Staphylococcus aureus (MRSA) Acquisition in Roommate Contacts of Patients Colonized or Infected With MRSA in an Acute-Care Hospital

Abstract: Roommates of patients with MRSA are at significant risk for becoming colonized. Further study is needed of the impact of hospital antimicrobial formulary decisions on the risk of acquisition of MRSA.

Cited by 55 publications

References 37 publications

Transmission of Methicillin-Resistant Staphylococcus aureus to Household Contacts

Transmission of Methicillin-Resistant Staphylococcus aureus to Household Contacts

Empfehlungen zur Prävention und Kontrolle von Methicillin-resistenten Staphylococcus aureus-Stämmen (MRSA) in medizinischen und pflegerischen Einrichtungen

Epidemiology of Staphylococcus aureus Harboring the mecA or Panton-Valentine Leukocidin Genes in Hospitals in Java and Bali, Indonesia

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