Risk factors for non-specific low back pain in older people: a systematic review with meta-analysis

Felício, Diogo Carvalho; Filho, José Elias; Oliveira, Túlio Medina Dutra de; Pereira, Daniele Sirineu; Rocha, Vítor Tigre Martins; Barbosa, Juliana Magalhães Machado; Assis, Marcella Guimarães; Malaguti, Carla; Pereira, Leani Souza Máximo

doi:10.1007/s00402-021-03959-0

Cited by 8 publications

(9 citation statements)

References 33 publications

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“…21 In addition, BMI and smoking have been reported as risk factors for nonspecific back pain (BP) and may therefore represent potential confounders. 2,4 Thus, we performed a multivariate analysis to confirm whether recovery of myelopathic symptoms was indeed associated with improvement in LBP. [2][3][4]23 Better preoperative NDI as a positive prognostic factor for MCID achievement may be partially explained by the fact that some domains may detect underlying LBP risk factors that are not alleviated by cervical spine surgery.…”

Section: Discussionmentioning

confidence: 99%

“…2,4 Thus, we performed a multivariate analysis to confirm whether recovery of myelopathic symptoms was indeed associated with improvement in LBP. [2][3][4]23 Better preoperative NDI as a positive prognostic factor for MCID achievement may be partially explained by the fact that some domains may detect underlying LBP risk factors that are not alleviated by cervical spine surgery. Although the direct relationship between the NDI and LBP has not been studied, each domain has been shown to have a different impact on the quality of life.…”

Section: Discussionmentioning

confidence: 99%

“…Since the occurrence of LBP is complex and multifactorial, our multivariate analysis adjusted for the following variables based on previous literature: age, sex, body mass index (BMI), etiology of cervical spine disease, and smoking habit. [2][3][4]21 Statistical analysis was performed using SAS version 9.4 (SAS Inc., Cary, NC). P-values of <0.05 were considered significant.…”

Section: Statistical Analysesmentioning

confidence: 99%

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Coexisting Lower Back Pain in Patients With Cervical Myelopathy

Nakarai,

Kato,

Hirao

et al. 2024

Clinical Spine Surgery

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Study Design: Retrospective cohort study Objective: The aim of the present study is to investigate the coexisting lower back pain (LBP) in patients with cervical myelopathy and to evaluate changes in LBP after cervical spine surgery. Summary of Background Data: Only a few studies with a small number of participants have evaluated the association between cervical myelopathy surgery and postoperative improvement in LBP. Methods: Patients who underwent primary cervical decompression surgery with or without fusion for myelopathy and completed preoperative and 1-year postoperative questionnaires were reviewed using a prospectively collected database involving 9 tertiary referral hospitals. The questionnaires included the patient-reported Japanese Orthopaedic Association (PRO-JOA) score and Numerical Rating Scales (NRS). The minimum clinically important difference (MCID) for NRS-LBP was defined as >30% improvement from baseline. Patient demographics, characteristics, and PRO-JOA score were compared between patients with and without concurrent LBP, and the contributor to achieving the MCID for LBP was analyzed using logistic regression analysis. Results: A total of 786 consecutive patients with cervical myelopathy were included, of which 525 (67%) presented with concurrent LBP. LBP was associated with a higher body mass index (P<0.001) and worse preoperative PRO-JOA score (P<0.001). Among the 525 patients with concurrent LBP, the mean postoperative NRS-LBP significantly improved from 4.5±2.4 to 3.4±2.7 (P<0.01) postoperatively, with 248 (47%) patients reaching the MCID cutoff. Patients with a PRO-JOA recovery rate >50% were more likely to achieve MCID compared with those with a recovery rate <0% (adjusted odd ratio 4.02, P<0.001). Conclusions: More than 50% of patients with myelopathy reported improvement in LBP after cervical spine surgery, and 47% achieved the MCID for LBP, which was positively correlated with a better PRO-JOA recovery rate. Treating cervical myelopathy in patients with concomitant LBP may be sufficient to mitigate concomitant LBP. Level of Evidence: Level Ⅲ

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Statistical Analysesmentioning

confidence: 99%

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Coexisting Lower Back Pain in Patients With Cervical Myelopathy

Nakarai,

Kato,

Hirao

et al. 2024

Clinical Spine Surgery

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“…Chronic non-specific low back pain (CNLBP) is a type of low back pain that persists for 12 weeks or longer and is not due to any specific pathology (6). With the increase in the elderly population, the prevalence of CNLBP also increases, resulting in physical limitations, reduced quality of life, balance problems, and psychosocial disorders (7,8).…”

Section: Introductionmentioning

confidence: 99%

Kronik Non-Spesifik Bel Ağrılı Yaşlılarda Ağrı ve Depresyon Düzeylerinin Yaşam Kalitesi ile İlişkisi Varmıdır?

Yaman

AKSOY

Leblebicier

et al. 2023

Osmangazi̇ Journal of Medicine

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This study aimed to investigate the relationship between pain severity and depression level and quality of life in elderly patients with chronic non-specific low back pain (CNLBP) and determine the effect of age group on the quality of life, pain severity and depression symptom levels of patients. Evaluation parameters were obtained using scales specific to geriatric patients. Pain severity, depression, and quality of life were evaluated using the Geriatric Pain Measure (GPM), Geriatric Depression Scale (GDS), and World Health Organization Quality of Life Questionnaire-Older Adults Module (WHOQOL-OLD), respectively. The study included a total of 231 patients with CNLBP (age ≥65 years), of whom 62.3% (n=144) were female and 37.7% were male (n=87). There was a moderate correlation between the patients’ GDS and GPM scores (r=0.53; p<0.05). GDS also had a moderate correlation with the ‘past-present-and-future activities’ (r=-0.52) and ‘social participation’ (r=-0.48) subdomains of WHOQOL-OLD (p<0.05). According to age groups, the only statistically significant difference was observed in ‘sensory abilities’ (p<0.05). Quality of life is negatively affected by the level of depression and pain intensity in elderly individuals with CNLBP. Evaluation of pain severity and depressive symptom levels in elderly patients with CNLBP may contribute to the establishment of an elderly population with improved quality of life and treatment approach. There is a need for further studies to reveal the reasons for poorer quality of life and increased depression and pain.

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“…For example, older age, smoking, insufficient physical activity, use of alcohol, and obesity increase the risk of BD, and of cardiovascular and metabolic diseases ( 1 , 2 ); height loss with aging increases the risk of BD, and of gastroesophageal reflux disease ( 3 ); delivery rank in women, hypertension or lower education increase the risk of BD and of urinary incontinence ( 4 ); long-term smoking is a risk factor for BD and for chronic obstructive pulmonary disease (COPD) ( 2 , 5 ). Furthermore, various NCIs themselves increase the risk of BD, for example, asthma or COPD ( 6 ), depression ( 7 ), urinary dysfunction ( 8 ), different conditions associated with chronic systemic inflammation ( 9 ), although the association of proinflammatory biomarkers and BD is not consistent across the literature ( 10 ). In addition to similar risk factors and mutual causation, more comorbidity between BD and other NCIs may, of course, be caused by common etiologic factors or pathogenetic mechanisms, of which many do not necessarily have to be known.…”

Section: Introductionmentioning

confidence: 99%

Chronic Multimorbidity of Low Back Pain or other Chronic Back Disorders in the Republic of Croatia

Marunica Karšaj

2023

ACC

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The aim was to assess the prevalence of chronic multimorbidity in patients with chronic low back pain or other chronic back disorders (BD). We analyzed data from the population-based cross-sectional European Health Interview Survey (EHIS) performed in the Republic of Croatia 2014-2015 by the Croatian Institute of Public Health. Outcome was the point-prevalence of chronic multimorbidity defined as having ≥2 chronic illnesses out of 14 contained in the EHIS questionnaire, after adjustment for ten sociodemographic, anthropometric and lifestyle confounders. Amoung fourteen targeted illnesses were asthma, allergies, hypertension, urinary incontinence, kidney diseases, coronary heart disease or angina pectoris, neck disorder, arthrosis, chronic obstructive pulmonary disease, diabetes mellitus, myocardial infarction, stroke, depression, and the common category "other". We analyzed data on 268 participants with BD and 511 without it. Participants with BD had a significantly higher relative risk of any chronic multimorbidity (RRadj=2.12; 95% CI 1.55, 2.99; p<0.001), as well as of non-musculoskeletal chronic multimorbidity (RRadj=2.29; 95% CI 1.70, 3.08; p=0.001) than participants without BD. All chronic comorbidities except for asthma and liver cirrhosis were significantly more prevalent in participants with BD than in participants without BD. In the population with BD, the participants with multimorbidity had three to four times higher odds for unfavorable self-reported health outcomes than the participants with no comorbid conditions, whereas the existence of only one comorbidity was not significantly associated with a worse outcome compared to the population with no comorbidities. In conclusion, the population suffering from BD has a higher prevalence of chronic multimorbidity than the population without BD and this multimorbidity is associated with unfavorable health outcomes.

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Risk factors for non-specific low back pain in older people: a systematic review with meta-analysis

Cited by 8 publications

References 33 publications

Coexisting Lower Back Pain in Patients With Cervical Myelopathy

Coexisting Lower Back Pain in Patients With Cervical Myelopathy

Kronik Non-Spesifik Bel Ağrılı Yaşlılarda Ağrı ve Depresyon Düzeylerinin Yaşam Kalitesi ile İlişkisi Varmıdır?

Chronic Multimorbidity of Low Back Pain or other Chronic Back Disorders in the Republic of Croatia

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