Risk Factors for Perioperative Hidden Blood Loss After Intertrochanteric Fracture Surgery in Chinese Patients: A Meta-Analysis

Abstract

Study Design A meta-analysis Introduction To perform a meta-analysis to explore the risk factors of perioperative hidden blood loss (HBL) in the treatment of intertrochanteric fracture for Chinese patients. Significance An extensive search of the literature was performed in the English databases of PubMed, Embase, and Cochrane Library and the Chinese databases of CNKI and WAN FANG (up to July 2021). We collected factors including demographic data and surgical factors. Data analysis was conducted with RevMan 5.3 and STATA 12.0. Results Finally, we collected 7 studies including 1377 patients in the final analysis. In our study, female patients ( P <.00001), hypertension ( P =.008), time from injury to operation (<2 days, P =.02), operation time (≥60 mins, P =.001), fracture type (A2.2 to A3.3, P <.00001), and without anticoagulation ( P <.00001) were found to be associated with perioperative HBL in Chinese patients receiving the treatment of the intertrochanteric fracture. However, anesthesia, ASA classification, and body mass index were not associated with perioperative HBL. Conclusions In our study, female patients, hypertension, time from injury to operation (<2 days), operation time (≥60 mins), fracture type (A2.2 to A3.3), and without anticoagulation were related to increased risks of perioperative HBL in Chinese patients receiving the treatment for the intertrochanteric fracture. We hope this article can guide for surgeons to reduce perioperative HBL as far as possible in the treatment of intertrochanteric fracture.

Risk Factors Analysis and Nomogram Model Establishment of Hidden Blood Loss in Overweight and Obese Elderly Patients After Total Hip Arthroplasty

“…The influence of hypertension on postoperative HBL remains controversial. 12 , 20 , 21 Patients with hypertension have more HBL after surgery due to their higher blood pressure and fragile capillaries, which can result in more small bleeding spots caused by intraoperative manipulation. 21 , 22 In our study, hypertensive patients had less HBL compared to normotensive patients.…”

Commentary on “Risk Factors for Perioperative Hidden Blood Loss After Intertrochanteric Fracture Surgery in Chinese Patients: A Meta-Analysis”

“…We have read the recent article with great interest entitled “Risk Factors for Perioperative Hidden Blood Loss After Intertrochanteric Fracture Surgery in Chinese Patients: A Meta-Analysis” by Wang et al 1 The authors of the study purposed to explore the risk factors of perioperative hidden blood loss in the treatment of intertrochanteric fracture for Chinese patients. While we deeply appreciate the efforts made by the authors in this study, there are some concerns that we would like to address which may induce some improvements in the study.…”