Risk Factors for Pre-eclampsia in Multiparous Women in Lagos, Nigeria

Adegbesan-Omilabu, Maymunah Adesola; Okunade, Kehinde Sharafadeen; Gbadegesin, Abidoye; Akinsola, O J

doi:10.7439/ijbr.v5i4.564

Cited by 3 publications

(2 citation statements)

References 16 publications

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“…It is a multi-systemic disorder with both maternal and fetal manifestations, complicating 2-10% of all pregnancies globally. [1][2][3][4][5] Preeclampsia has been a major challenge to obstetric practice as it is one of the most common and dangerous complications of pregnancy associated with high maternal and perinatal morbidity and mortality especially in developing countries like Nigeria. 1,3,6 The prevalence of preeclampsia in Nigeria ranges between 2% and 16.7%.…”

Section: Introductionmentioning

confidence: 99%

The role of umbilical artery doppler indices in predicting perinatal outcome in preeclampsia

Irowa¹,

Hameed²,

Issac³

et al. 2023

Int J Res Med Sci

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Background: Preeclampsia currently accounts for the majority of causes of perinatal morbidity and mortality. Umbilical artery Doppler (UAD) is a non-invasive effective method of antenatal fetal surveillance for early detection and prevention of potentially adverse perinatal outcome in preeclampsia. The objective of this study is to predict adverse perinatal outcome using UAD in Preeclampsia. Methods: This was a prospective cohort study in which 170 consecutively consenting women with preeclampsia were recruited. An UAD was done using Voluson P8 ultrasound. The pulsatility index, resistance index, systolic/diastole ratio. Reduced end diastolic flow, absent end diastolic flow and reversed end diastolic flow were measured. The participants were divided into two groups based on UAD indices findings. Both groups were followed up to determine their perinatal outcomes.The data was analyzed using SPSS version 20.0 for windows (IBM SPSS Inc, Chicago, IL, USA). Categorical variables were analyzed using Chi-Square ( 2) test and Fisher's exact test p<0.05 was considered statistically significant. Specificity, sensitivity, PPV and NPV were determined. Results: The sensitivity, specificity, PPV, and NPV of umbilical artery Doppler in predicting adverse perinatal outcomes was 68.5%, 59.7%, 74.7%, and 52.1% respectively. Conclusions: Although the use of UAD indices in this study showed modest predictive values for adverse perinatal outcome in preeclampsia, it’s use should be combine with other methods of antenatal fetal surveillance to prevent adverse perinatal outcome.

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Section: Introductionmentioning

confidence: 99%

The role of umbilical artery doppler indices in predicting perinatal outcome in preeclampsia

Irowa¹,

Hameed²,

Issac³

et al. 2023

Int J Res Med Sci

View full text Add to dashboard Cite

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“…Thus, the incidence of seizures in patients with severe preeclampsia and eclampsia should be avoided as it causes 5% or higher mortality (Omilabu et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

Laboratory Analysis of Blood in Pregnant Women With Pre-Eclampsia in the Delivery Room of Rsud Dr. R. Koesma Tuban.

Qonitun

Munir²,

hidayah³

2023

IMHSJ

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30-40% of maternal deaths in Indonesia were caused by pre-eclampsia in 2018. Preeclampsia is a specific syndrome in pregnancy that can cause liver problems. Disorders can be characterized by abnormal laboratory results in the liver enzymes while in the kidney is indicated by the presence of proteinuria. Organ disorders can cause morbidity and death of the mother and fetus. This study aims to analyze the results of blood laboratory in pregnant women with preeclampsia in the delivery room of RSUD dr.R Koesma Tuban in 2020. Method: The research design is correlation analysis. The population of all pregnant women with preeclampsia in the delivery room at RSUD dr. R Koesma Tuban from January to June 2020, with a total of 102 people, a sample of 52 people used simple random sampling. The independent variable is preeclampsia, the dependent variable is the platelet level. Using the chi square test with a significance level of p<0.05. Results: most of the pregnant women with severe preeclampsia 39 (75%), almost all 42 (81%) platelet levels were in the normal category. With a significance value of 0.115, then H1 is rejected, meaning that there is no relationship between platelet laboratory levels in pregnant women and preeclampsia in the maternity ward of RSUD DR. Koesma Tuban. Conclusion: there is no relationship between preeclampsia and platelet levels. So that it is hoped that research can be carried out on the causes of preeclampsia and other laboratory results

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