Risk Factors for Surgical Site Infections in Abdominal Surgery: A Study in Nepal

Giri, Subarna; Kandel, Bishnu Prasad; Pant, Sagun Ballav; Lakhey, Paleswan Joshi; Singh, Yogendra; Vaidya, Pradeep

doi:10.1089/sur.2012.108

Cited by 29 publications

(48 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The risk ratio was also true when a braided was used. These findings are concordant with those in Nepal [ 2 ].…”

Section: Discussionsupporting

confidence: 92%

“…This contrasts with the overall SSI rate in mainland China which is at 4.5% [ 5 ] and that in Seoul, South Korea, at 3.3% [ 6 ] and that in the US at 2-3% [ 7 ]. In Ethiopia, SSI rates were found at 10.6% [ 8 ] whereas in a private hospital in Kenya incident rates of 7.0% were found [ 3 ] and the overall SSI rate in Nepal and Tanzania was 23% and 26%, respectively [ 2 , 9 ].…”

Section: Discussionmentioning

confidence: 99%

“…SSIs remain a major cause of morbidity and death among the operated patients and continue to represent about a fifth of all healthcare-associated infections [ 1 ]. Although at least 5% of patients develop an SSI after surgery [ 2 ], these infections seem to cause remarkably little concern, remaining largely unreported in the media.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Incidence and Etiology of Surgical Site Infections among Emergency Postoperative Patients in Mbarara Regional Referral Hospital, South Western Uganda

Lubega

Bazira

Lucy

2017

Surgery Research and Practice

View full text Add to dashboard Cite

Background. This prospective hospital based study was conducted to determine the incidence, risk factors, and causative agents of surgical site infection their susceptibility to among 114 emergency postoperative patients at the Mbarara Regional Referral Hospital between September 2014 and January 2015. Methods. Consented patients were consecutively enrolled and their preoperative, intraoperative, and postoperative data were collected. Follow-ups were done in the surgical outpatient clinics. Wound specimens were collected and processed as per Sops; susceptibility testing was done using the Kirby-Bauer disc diffusion technique. Data was analyzed using STATA 11.0. Results. Overall SSI incidence was 16.4%: 5.9% superficial and 47.1% deep and organ space SSIs each. Klebsiella pneumoniae was the most predominant organism (50%) followed by Staphylococcus aureus (27.8%). E. coli and P. aeruginosa both accounted for 11.1%. Wound class (p = 0.009), anaemia (p = 0.024), low serum albumin (p = 0.046), and property of suture material used (p = 0.006) were significantly associated with SSIs. All organisms had 100% resistance to ampicillin, tetracycline, septrin, and erythromycin. Ciprofloxacin and ceftriaxone are highly sensitive to all organisms. Conclusion. The incidence of SSI in this hospital is very high. Klebsiella pneumoniae is the predominant cause. Ciprofloxacin are very potent antibiotics against organisms that cause SSI.

show abstract

“…The risk ratio was also true when a braided was used. These findings are concordant with those in Nepal [ 2 ].…”

Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Incidence and Etiology of Surgical Site Infections among Emergency Postoperative Patients in Mbarara Regional Referral Hospital, South Western Uganda

Lubega

Bazira

Lucy

2017

Surgery Research and Practice

View full text Add to dashboard Cite

show abstract

“…Earlier prevalence studies have shown that Staphylococcus aureus and Pseudomonas aeruginosa were the most isolated organisms in post-operative wound infections accounting for 20–40% and 5–15% respectively [ 10 ], with the variation indicating geographical and temporal relationships [ 11 ]. Nosocomial infections and post-operative wound sepsis have remained a major cause of morbidity and death among the operated patients [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

Bacterial Aetiology and Antibiotic Susceptibility Profile of Post-Operative Sepsis among Surgical Patients in a Tertiary Hospital in Rural Eastern Uganda

Masifa

Iramiot

Muhindo

et al. 2018

MRJI

View full text Add to dashboard Cite

Background:Post-operative wound sepsis remains a surgical challenge of public health concern constituting approximately 20% of the health care-associated nosocomial infections. This study aimed at determining the prevalence and antimicrobial resistance patterns of bacterial pathogens isolated from post-operative wound infections at Mbale Regional Referral Hospital.Materials and Methods:This was a descriptive cross-sectional study conducted from June to October 2015. Study participant samples were sub-cultured upon reception in the Microbiology laboratory and the isolated bacterial pathogens were analysed. Phenotypic antimicrobial susceptibility profiles were determined using the Kirby-Bauer method. Interpretation of the zone diameters was done following the Clinical and Laboratory Standards Institute guidelines. Phenotypic screening for Methicillin-resistant Staphylococcus aureus (MRSA) was performed using oxacillin (1 μg). D-test was also performed for phenotypic screening of inducible clindamycin resistant Staphylococcus aureus, Data were entered into Microsoft Excel and analysed using IBM SPSS statistics (version 16).Results:Overall post-operative sepsis was 69/80 (86.2%) with Staphylococcus aureus as the most predominant organism 41/104 (39.4%) followed by Escherichia coli 22/104 (21.2%) and Klebsiella species 15/104 (14.4%). Of the 41/104 isolated Staphylococcus aureus, 27/41(65.9%) were MRSA strains and 5/41 (12.2%) were inducible clindamycin resistant Staphylococcus aureus strains. The isolated Staphylococcus aureus was resistant to multiple drugs though susceptible to vancomycin and clindamycin. In addition, none of the isolated Enterococci species was vancomycin resistant. Although most of the isolated Gram-negative organisms were sensitive to imipenem, resistance was observed for tetracycline, trimethoprim/sulphamethoxazole, and ceftriaxone.Conclusion:Staphylococcus aureus was the most common causative agent associated with postoperative sepsis with most of the strains being MRSA. Multi-drug resistance was observed in 63/104 (60.6%) of the isolated organisms in our study. Hence the need to better develop and strengthen antimicrobial stewardship programs as well as to understand the carriage of antimicrobial resistance genes among these organisms.

show abstract

“…Various authors have evaluated the incidence and risk factors for surgical site infection in surgical abdominal wounds. Giri S et al, 10 observed that out of 230 patients included, 53 were identified as having a SSI, resulting in an overall rate of SSI of 23%. Nwankwo E et al, 11 in their study observed that out of 2880 patients studied, 585 (20.3%) developed SSI.…”

Section: Prevalence Of Surgical Site Infectionmentioning

confidence: 99%

A Study of Incidence and Risk Factors in Post Operative Abdominal Wound Infection in Tertiary Care Centre

Thombare

Joshi

2019

mvpjms

View full text Add to dashboard Cite

show abstract

Risk Factors for Surgical Site Infections in Abdominal Surgery: A Study in Nepal

Cited by 29 publications

References 30 publications

Incidence and Etiology of Surgical Site Infections among Emergency Postoperative Patients in Mbarara Regional Referral Hospital, South Western Uganda

Incidence and Etiology of Surgical Site Infections among Emergency Postoperative Patients in Mbarara Regional Referral Hospital, South Western Uganda

Bacterial Aetiology and Antibiotic Susceptibility Profile of Post-Operative Sepsis among Surgical Patients in a Tertiary Hospital in Rural Eastern Uganda

A Study of Incidence and Risk Factors in Post Operative Abdominal Wound Infection in Tertiary Care Centre

Contact Info

Product

Resources

About