Risk Factors of Secondary Vertebral Compression Fracture After Percutaneous Vertebroplasty or Kyphoplasty: A Retrospective Study of 650 Patients

Chen, Ziqi; Wu, Yanping; Ning, Sheng‐Hua; Ma, Tao; Wu, Zhanyong

doi:10.12659/msm.915312

Cited by 36 publications

(35 citation statements)

References 30 publications

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“…The resultant spinal sagittal decompensation, will lead to persistent lower back pain. 13 Consistent with our findings, a previous study also suggested an association between thoracolumbar fascia injury and postoperative residual lower back pain after PV. 8 However, unlike the previous study which found that patients with thoracolumbar fascia injury benefitted from PV in terms of pain VAS scores, 8 this present study found thoracolumbar fascia injury was a high-risk factor for poor pain relief after PV.…”

Section: Discussionsupporting

confidence: 93%

“…12 Our findings that low BMD was a risk factor for pain is not surprising since previous studies have confirmed that osteoporosis is a risk factor for recurrent vertebral fractures after PV. 2,10,13 In addition, due to the collapse of multiple vertebral bodies, patients with osteoporosis are prone to kyphosis and secondary sagittal imbalances. 2,12 In these patients, nonphysiological compensation can easily lead to back muscle strain and intermittent lower back pain.…”

Section: Discussionmentioning

confidence: 99%

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Risk factors for thoracolumbar pain following percutaneous vertebroplasty for osteoporotic vertebral compression fractures

et al. 2021

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Objective To explore possible risk factors for poor outcomes following percutaneous vertebroplasty (PV) for painful osteoporotic compression fractures of thoracolumbar vertebra. Methods This was a retrospective review of data from patients who underwent PV at our institution over a ten-year period to evaluate the association between possible risk factors and thoracolumbar pain (T11-L2). According to the difference between pre- and post-operative visual analogue scale (VAS) scores for pain, patients were separated into poor relief (PR; <4) and good relief (GR; ≥4) of pain. Results Of the 750 patients identified, 630 (PR group, n =310; GR group, n = 320) fulfilled the eligibility criteria. Multivariate binary logistic analysis showed that bone mineral density (BMD), >2 fractured vertebral bodies, maldistribution of bone cement, <5 ml bone cement injected into a single vertebral body and thoracolumbar fascia injury prior to surgery were independent risk factors associated with thoracolumbar pain following PV. Conclusion Although prospective controlled studies are required to confirm our results, this review suggests that the above factors should be taken into account when selecting patients for PV.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Risk factors for thoracolumbar pain following percutaneous vertebroplasty for osteoporotic vertebral compression fractures

et al. 2021

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“…To clarify the risk factors for SVCF, we analyzed clinical and radiographical parameters including gender, age, BMI, number of primary fractures, primary treatment (PVP/PKP or conservative treatment), non-spinal fracture history, primary fracture at the TL junction, steroid use, bisphosphonate therapy, and HU value of L1. Elderly postmenopausal women are considered at increased risk of refracture, and previous studies showed that old age was independently associated with incidence of refracture, while our study reported that there was no significant difference in terms of age and gender (14). It is commonly thought that obesity leads to higher lumbar spine load, however, BMI did not reach significance in our study.…”

Section: Discussioncontrasting

confidence: 89%

Risk Factors for Refracture following Primary Osteoporotic Vertebral Compression Fractures

Rong

Wang

et al. 2021

Pain Phys

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Background: In the aging population, osteoporosis and related complications have become a global public health problem. Osteoporotic vertebral compression fractures are among the most common type of osteoporotic fractures and patients are at risk of secondary vertebral compression fracture. Objectives: To identify risk factors for secondary vertebral compression fracture following primary osteoporotic vertebral compression fractures. Study Design: Retrospective study. Setting: Department of Orthopedic, an affiliated hospital of a medical university. Methods: This retrospective cohort study evaluated the risk factors for secondary vertebral compression fracture in 317 consecutive patients with systematic osteoporotic vertebral compression fractures who received percutaneous vertebroplasty and kyphoplasty or conservative treatment. Patients were divided into secondary vertebral compression fracture (n = 43) and non- secondary vertebral compression fracture (n = 274) groups. We retrospectively analyzed clinical characteristics and radiographic parameters, including gender, age, body mass index, number of primary fractures, primary treatment (percutaneous vertebroplasty and kyphoplasty or conservative treatment), nonspinal fracture history before primary fracture, primary fracture at the thoracolumbar junction, steroid use, bisphosphonate therapy, and Hounsfield units value of L1. Results: Comparison between the groups showed significant differences in age (P = 0.001), nonspinal fracture history (P < 0.001), and Hounsfield units value of L1 (P < 0.001). The receiver operating characteristic curves demonstrated that the optimal thresholds for age and Hounsfield units value of L1 were 75 (sensitivity: 55.8%; specificity: 67.5%) and 50 (sensitivity: 88.3%; specificity: 67.4%), respectively. In multivariate logistic regression analysis, nonspinal fracture history (OR = 6.639, 95% CI = 1.809 – 24.371, P = 0.004) and Hounsfield units value of L1 < 50 (OR = 15.260, 95% CI = 6.957 – 33.473, P < 0.001) were independent risk factors for secondary vertebral compression fracture. Limitations: The main limitation is the retrospective nature of this study. Conclusion: Patients with low Hounsfield units value of L1 or non-spinal fracture history are an important population to target for secondary fracture prevention. Key words: Risk factor, vertebral, secondary fracture, osteoporosis

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“…10.4% for men and 6.7%~19.3% for women. Therefore, age and bone mass loss are high-risk factors for fracture [5]. Although osteoporosis is one of the important risk factors of vertebral compression fractures, not all vertebral compression fractures have obvious osteoporosis [6].…”

Section: Introductionmentioning

confidence: 99%

Comparison of Percutaneous Kyphoplasty and Percutaneous Pedicle Screw Fixation for the Treatment of Osteopenic Thoracolumbar Vertebral Compression Fractures

Zhang¹,

Yi²,

Xia³

et al. 2020

Preprint

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BACKGROUND: Osteoporotic vertebral compression fractures (OVCFs) have a high incidence, which have attracted wide attention from society. However, few scholars have conducted researches on osteopenic vertebral compression fractures (osteopenic VCFs). Our research has compared the clinical and imaging effects of percutaneous kyphoplasty (PKP) and percutaneous pedicle screw fixation (PPSF) in the treatment of Osteopenic thoracolumbar vertebral compression fractures (Osteopenic VCFs).METHODS: From December 2018 to September 2020, 70 patients with osteopenic VCFs who had undergone PKP and PPSF surgeries at our medical center were reviewed retrospectively. All patients were divided into PKP group (n=38) and PPSF group (n=32). Clinical data including clinical and radiological evaluation results were performed pre- and postoperatively.RESULTS: The operation time, bleeding volume, postoperative bedtime, and hospitalization period in PKP group were lower than those in PPSF group (P<0.05). The visual analogue scale (VAS) and Oswestry Disability Index (ODI) of two groups in the last follow-up were lower than those before the operation (P<0.05). On the 3rd day after the operation, VAS and ODI in PPSF group were higher than those in PKP group (P<0.05). The anterior height of injured vertebrae (AH) of two groups was recovered compared with that before the operation. Compared with two groups in each period, there was no obvious difference in AH or the height restoration of injured vertebrae (HR) (P>0.05). The anterior height ratio of injured vertebrae (AHR) of PPSF group was higher than that of PKP group after the operation (P<0.05). The kyphosis angle (KA) in PPSF group was smaller than PKP group after the operation (P<0.05). All patients in PPSF group have achieved bony healing at the last follow-up.CONCLUTIONS: Both PPSF and PKP can achieve satisfactory clinical results in the treatment of Osteopenic VCFs. The short-term clinical effect of PKP is better than that of PPSF, but the latter has better long-term results, including the correction and maintenance of vertebral height and the acquisition of osseous fusion.

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Risk Factors of Secondary Vertebral Compression Fracture After Percutaneous Vertebroplasty or Kyphoplasty: A Retrospective Study of 650 Patients

Cited by 36 publications

References 30 publications

Risk factors for thoracolumbar pain following percutaneous vertebroplasty for osteoporotic vertebral compression fractures

Risk factors for thoracolumbar pain following percutaneous vertebroplasty for osteoporotic vertebral compression fractures

Risk Factors for Refracture following Primary Osteoporotic Vertebral Compression Fractures

Comparison of Percutaneous Kyphoplasty and Percutaneous Pedicle Screw Fixation for the Treatment of Osteopenic Thoracolumbar Vertebral Compression Fractures

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