1985
DOI: 10.1002/1097-0142(19850215)55:4<907::aid-cncr2820550433>3.0.co;2-5
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Risk factors of squamous cell carcinoma of the skin. A case-control study in the montreal region

Abstract: A matched case‐control study was undertaken to assess the relative risk associated with known and suspected risk factors of squamous cell carcinoma of the skin among patients in the Montreal region. Three hundred eleven cases histologically diagnosed in 1977 and 1978 in 12 hospitals and meeting strict definition criteria were identified. With the exception of six cases, two controls were matched to each case for sex, age, and hospital of diagnosis. A logistic regression analysis was done. The known host risk f… Show more

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Cited by 149 publications
(86 citation statements)
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“…In our study, current smokers were 4.3 (95% confidence interval (CI), 2.9 -6.4) times more likely than never smokers to have one of these cancers (including vaginal cancers). Studies on smoking and SCC skin have had mixed results (Aubry and MacGibbon, 1985;Karagas et al, 1992;Grodstein et al, 1995;Lear et al, 1998;De Hertog et al, 2001;Odenbro et al, 2005). Current smokers were also at 3.9 (95% CI, 2.1 -7.3) times the risk of SCC of the skin of never smokers, which is not dissimilar to estimates in other case -control studies where risks ranged from 2.3 to 3.3 (Aubry and MacGibbon, 1985;De Hertog et al, 2001).…”
Section: Discussionmentioning
confidence: 99%
“…In our study, current smokers were 4.3 (95% confidence interval (CI), 2.9 -6.4) times more likely than never smokers to have one of these cancers (including vaginal cancers). Studies on smoking and SCC skin have had mixed results (Aubry and MacGibbon, 1985;Karagas et al, 1992;Grodstein et al, 1995;Lear et al, 1998;De Hertog et al, 2001;Odenbro et al, 2005). Current smokers were also at 3.9 (95% CI, 2.1 -7.3) times the risk of SCC of the skin of never smokers, which is not dissimilar to estimates in other case -control studies where risks ranged from 2.3 to 3.3 (Aubry and MacGibbon, 1985;De Hertog et al, 2001).…”
Section: Discussionmentioning
confidence: 99%
“…We did, however, corroborate a previous report of the association between increased alcohol consumption and past smoking with a higher prevalence of NMSC (Aubry and MacGibbon, 1985;Grodstein et al, 1995;Veierod et al, 1997;De Hertog et al, 2001). We also found that past smoking was associated with an increased prevalence of NMSC, although current smokers had the lowest rate of NMSC.…”
Section: Discussionmentioning
confidence: 95%
“…43,44 In one of the largest studies, Grodstein et al 45 prospectively examined the risk of developing cutaneous SCC in relation to skin type, sun exposure, cigarette smoking, and other factors. They showed during an 8-year observation of a cohort of 107,900 predominantly white young women that smokers had a 50% greater chance of developing cutaneous SCC than nonsmokers (RR 1.5; 95% CI 1.1-2.1).…”
Section: Squamous Cell Carcinomamentioning
confidence: 99%