“…Then feed the X s, j into the function w s , and its output (L ′ s ,C ′ s ) has joint distribution H ′ s . For example, this is exactly the setting of the RISMC studies in Sherry, Gabor, and Hess (2013) and Dube et al (2014), where w s represents a detailed nuclear-specific computer code modeling the progression of a hypothesized accident in a NPP; see Hess et al (2009) for a survey of widely used codes in the nuclear industry. In general, a code run involves numerically solving a system of differential equations, which can require enormous computational effort, making variance reduction crucial to reduce the number of runs needed to achieve an acceptable precision.…”