Abstract-Now the automobile manufacturing industry gradually developed into a pillar industry in Guangxi, it brings the opportunity to Guangxi, at the same time, it also has a certain risk. This paper focuses on the supply chain risk assessment of automobile manufacturing enterprises in this region, starting from the present situation of supply chain of automobile manufacturing enterprise, the supply chain risk of automobile enterprises is identified, and constructed the supply chain risk evaluation index system of automobile manufacturing enterprise, using fuzzy comprehensive evaluation method to evaluate the risk of supply chain in automobile manufacturing enterprises, finally, put forward the suggestion of reducing the risk of supply chain from the perspective of flexible management. It is expected to be helpful in the prevention of the risk of supply chain in automobile manufacturing enterprises.