Risk of Breast Cancer in Relation to Reproductive Factors in North-west of Iran, 2013-2014

Veisy, Afsaneh; Lotfinejad, Shirin; Salehi, Kamal; Zhian, Faegh

doi:10.7314/apjcp.2015.16.2.451

Cited by 24 publications

(20 citation statements)

References 28 publications

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“…While Age at menopause revealed in our study to have no association with breast diseases was consistent with a study done at north of Iraq which concluded that higher age at menopause was not a risk factor for postmenopausal breast cancer (Zangana & Garota, 2012). Otherwise a study conducted in Iran found that with increasing menopause age to over 50 years, odds of cancer incidence reached 50.1, and doubled at age over 60 years (Veisy, Lotfinejad, Salehi, & Zhian, 2015).…”

Section: Association Of Gynecological History and Obstetrical Historysupporting

confidence: 91%

Patterns of Breast Diseases Among Women Attending Breast Diseases Diagnosing Center in Erbil City/Iraq

Yousif¹,

Yacoub²

2018

GJHS

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Background and Objectives: Breast diseases in women, whether benign or malignant, are very commonly encountered. The pattern of breast diseases varies within countries. The aim of this study was to identify the patterns of breast diseases and their association with different variables in women attending breast diseases diagnosing center in Erbil city/Iraq. Material and Methods:A cross-sectional study conducted at breast diseases diagnosing center in Erbil city from 1 st of April till 1 st of December /2017. A random sample of 500 women of all age groups and with complete records was recruited. The women were classified according to their final diagnosis into 3 categories: normal, benign and malignant breast disease. The level of significance was <0.05. Results:Benign breast diseases diagnosed among (63%) women while malignant breast diseases comprised (13.2%).The most common presentation was mastalgia and mass (39.2%), mastalgia (37.6%), and mass alone (23.2%). Fibro-adenoma (26.2%) was the commonest benign condition with highest incidence (76.9%) in age group less than 20 years. Malignant breast diseases were increasing with age. Benign breast disease associated (p <0.001) with Nulliparity. Breast cancer reported (p <0.001) more among lactating women. Conclusions:Benign conditions are the most common diagnosis affecting mainly younger women. Breast cancer though diagnosed less frequently and affecting older age groups, yet its seriousness mandating a thorough assessment of women of different presentations especially that of mass alone or with mastalgia.

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Section: Association Of Gynecological History and Obstetrical Historysupporting

confidence: 91%

Patterns of Breast Diseases Among Women Attending Breast Diseases Diagnosing Center in Erbil City/Iraq

Yousif¹,

Yacoub²

2018

GJHS

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“…Especially the mother affected by breast cancer is considerably more responsible about three times higher than other family members. Like different world wide studies (Shankar, 2015;Veisy, 2015) this study has been noticed that the factors "Menarche start early", "Menopause stop late" are another two significant factors for Breast cancer. From our analysis it is found that women whose menarche is started early have more high risk (OR=3.500) than late started women.…”

Section: Discussionmentioning

confidence: 99%

“…Abnormal menstruation time also implies from at front to increase or create breast cancer. Menarche starts early before 12 years and Menopause stops at late after 55 years are mostly responsible to increase breast cancer patients Shankar, 2015;Veisy, 2015).…”

Section: Introductionmentioning

confidence: 99%

Association Assessment among Risk Factors and Breast Cancer in a Low Income Country: Bangladesh

Ahmed¹,

Asaduzzaman²,

Bashar³

et al. 2015

Asian Pacific Journal of Cancer Prevention

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Background: In the low incoming country Bangladesh, breast cancer is second most common neoplasm and is increasing at an alarming rate among females. Lack of awareness and illiteracy are contributory factors for late presentation and therefore mortality. Purpose: To examine associations of different factors with breast cancer mortality and to raise awareness among the women of society in Bangladesh. Materials and Methods: This descriptive case-control study was conducted on 160 participants from April 2011 till July 2014. Through a valid questionnaire covering personal and family history, data were collected by face to face interview. For analyzing correlations among factors with breast cancer data, binary logistic regression, Pearson's χ2-value, odd ratios and p-value tests were conducted with SPSS version 20. Results: The mean age of the patients was 43.0 (SD=±11.12). In ascending order the leading significant factors were hormone therapy (p<0.0000, OR=4.897), abortion (p<0.0001, OR=3.452), early start menarche (p<0.0002, OR=3.500), family history (p<0.0022, OR=3.235), and late menopause (p<0.0093, OR=3.674) with both χ2 test and logistic regression analyses. Non-significant factors were cancer experience, fatty food habits, marital status and taking alcohol. Conclusions: Regarding the investigation of this study, significant and insignificant factor's correlation visualization with breast cancer will be helpful to increase awareness among Bangladeshi women as well as all over the world.

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“…According to different epidemiologic studies in Iran, breast cancer is the first or second (after lung cancer) leading cause of death among cancerous women (Sadjadi et al, 2009;Kolahdoozan et al, 2010;Movahedi et al, 2012;Taghavi et al, 2012;Veisy et al, 2015) and the rate of death was increased from 3.933 to 4.92 per 100,000 cases between 2006 and 2010 (Enayatrad et al, 2015). Despite improvements in surgery and the use of adjuvant therapy, it continues to be fatal in many patients around the world.…”

Section: Introductionmentioning

confidence: 96%

Effect of Crocin on Cell Cycle Regulators in N-Nitroso-N-Methylurea-Induced Breast Cancer in Rats

Ashrafi

Bathaie

Abroun

et al. 2015

DNA and Cell Biology

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We previously showed the anticancer effect of crocin, a saffron carotenoid, in both breast and gastric cancers in animal models, but its mechanism of action is not clearly known, yet. In this study, the effect of crocin on cell cycle regulators is investigated. Female Wistar Albino rats were divided into two groups, with or without N-nitroso-N-methylurea (NMU) injection. After tumor formation, each group of rats was divided into two subgroups, receiving crocin or vehicle only. After 5 weeks, the rats were sacrificed and the tumors were retained for pathologic investigation and determination of the parameters. Before crocin treatment, the tumor volumes were 13.27±3.77 and 12.37±1.88, but at the end of the experiment, they were 23.66±8.82 and 11.91±2.27 in the control and crocin-treated groups, respectively. Pathologic investigation indicated the adenocarcinoma induction by NMU. Reverse transcription-polymerase chain reaction and Western blot analysis showed overexpression of cyclin D1 and p21(Cip1) in the NMU-induced breast tumors; however, the expression of both of them suppressed by crocin treatment. The previous studies indicated that crocin induces apoptosis in tumor tissue. In this study, we show that it also suppresses tumor growth and induces cell cycle arrest by downregulation of cyclin D1. In addition, crocin suppressed p21(Cip1) in a p53-dependent manner.

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Risk of Breast Cancer in Relation to Reproductive Factors in North-west of Iran, 2013-2014

Cited by 24 publications

References 28 publications

Patterns of Breast Diseases Among Women Attending Breast Diseases Diagnosing Center in Erbil City/Iraq

Patterns of Breast Diseases Among Women Attending Breast Diseases Diagnosing Center in Erbil City/Iraq

Association Assessment among Risk Factors and Breast Cancer in a Low Income Country: Bangladesh

Effect of Crocin on Cell Cycle Regulators in N-Nitroso-N-Methylurea-Induced Breast Cancer in Rats

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