Concerns regarding patients' radiation exposure have arisen in response to the rising use of medical imaging techniques, some of which include ionizing radiation. The purpose of this research was to analyze and assess patients' knowledge and attitudes about dosage and related dangers produced by Ionizing Radiation (IR) treatments. This was cross-sectional research including 377 consecutive patients done over a 4-month period at the radiology unit of Hospital Santa Rita de Cassia Vitoria in Najran for IR treatments utilizing self-administered surveys produced and provided to participants along with consents and instructions. Approximately three-quarters (60%) of the participants reported being unconcerned about undergoing radiological testing. If they can endure the sickness, the same number of patients would not undergo radiological exams. Approximately half of the respondents (50%) claimed that they would be dissatisfied if no more radioactive tests were necessary, and 52% did not believe that radiological treatments may pose risks and negative impacts on the body. Furthermore, more than half of the patients (53%) reported not understanding that radiological exams might increase cancer risk; 48% would not repeat radiological tests in six months; and around 69% were unaware of the necessity of Radiology for diagnostics. The study population has relatively poor knowledge and awareness of the dangers associated with Ionizing Radiation. As a result, there is a need to educate the general population, not only medical staff, concerning radiation exposure and its related hazards.