Risk of depression in patients with oral cancer: a nationwide cohort study in Taiwan

Kung, Ling-Yu; Li, Tsung-I; Chung, Chi‐Hsiang; Lee, Shiao-Pieng; Chen, Gunng-Shinng; Chien, Wu-Chien; Tzeng, Nian‐Sheng

doi:10.1038/s41598-021-02996-4

Cited by 12 publications

(4 citation statements)

References 69 publications

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“…[8][9][10] However, most patients who undergo surgery during the perioperative period (PPP) often experience psychological disorders, such as anxiety and depression. [11][12][13][14] Transcranial direct current stimulation (tDCS) is a safe, noninvasive, and painless treatment technique. [15][16][17][18] It applies low-intensity direct current using scalp electrodes overlying targeted cerebral cortical areas through the scalp.…”

Section: Introductionmentioning

confidence: 99%

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Transcranial direct current stimulation in the treatment of anxiety and depression in patients with oral cancer during perioperative period

et al. 2022

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This study retrospectively investigated the efficacy of transcranial direct current stimulation (tDCS) in the treatment of anxiety and depression in patients with oral cancer (OC) during the perioperative period (PPP). This retrospective study reviewed the electronic medical records of patients who underwent OC surgery and experienced anxiety and depression during PPP. The patients were divided into the treatment (n = 36) and control (n = 36) groups. The patients in the treatment group received tDCS, whereas those in the control group did not receive tDCS. The primary outcomes included the Self-rating Anxiety Scale (SAS) and the Self-rating Depression Scale (SDS). Secondary outcomes included adverse events (AEs). We analyzed the outcome data before and after treatment. After treatment, patients in the treatment group achieved greater relief in SAS (P < .01) and SDS (P < .01) scores than those in the control group. Regarding safety, no electronic medical records reported any AEs in this study. The results of this study showed that tDCS may help relieve depression and anxiety in patients with OC during PPP. However, high-quality prospective randomized controlled trials are required to confirm these findings.

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Section: Introductionmentioning

confidence: 99%

“…[8–10] However, most patients who undergo surgery during the perioperative period (PPP) often experience psychological disorders, such as anxiety and depression. [11–14]…”

Section: Introductionmentioning

confidence: 99%

Transcranial direct current stimulation in the treatment of anxiety and depression in patients with oral cancer during perioperative period

et al. 2022

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“…Urbanization levels 3 and 4 were defined as a population between 149,999 and 499,999, and <149,999, respectively. 31 …”

Section: Methodsmentioning

confidence: 99%

Association Between Endometriosis and Mental Disorders Including Psychiatric Disorders, Suicide, and All-Cause Mortality -A Nationwide Population-Based Cohort Study in Taiwan

Wang,

Lee,

Chung

et al. 2023

IJWH

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Objective A multitude of previous studies has substantiated that endometriosis correlated highly with psychiatric health. This study aims to investigate the association between endometriosis and psychiatric health. Methods Utilizing the National Health Insurance Research Database of Taiwan, 100,770 enrolled participants, including 20,154 patients with endometriosis and 80,616 in the control group (1:4), matched for age, and index date from Taiwan’s Longitudinal Health Insurance Database between January 1, 2000, and December 31, 2015. The Cox proportional regression model was used to compare the risk of mental disorders during the 16 years of follow-up after adjusting for confounding factors. Results Of the study patients, 4083 (20.26%) developed mental disorders; 9225 of the 80,616 controls (11.44%) developed mental disorders. The Cox regression demonstrated that, after adjusting for age, monthly income, urbanization level, etc., people with endometriosis are more likely to suffer from mental disorders compared to those without endometriosis (hazard ratio [HR]=2.131; 95% confidence interval [CI]= 1.531–2.788; p<0.001). The result illustrated that women over 40 years old had a more significant risk. Conclusion Compared to people without endometriosis, this study provides evidence that patients with endometriosis are at a 2.131-fold higher risk of developing mental disorders, especially in elder women. Regular psychiatric follow-up might be needed for those patients.

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“…Additionally, the patients diagnosed with anxiety, depression, bipolar disorders, sleep disorders, posttraumatic stress disorders (PTSD) or acute stress disorders (ASD), dementia, eating disorders, substance-related disorders (SRD), psychotic disorders, autism, other mental disorders, suicide, before 2000, or before their first visit for any one of the three diseases mentioned above were also excluded. 18 Of the total patients enrolled, 9954 participants with any of the three clinical manifestations of hyperandrogenism and 39,816 controls were matched for age and index date. Each enrolled participant was required to have made at least three outpatient visits or one inpatient episode in the 1-year study period for any of the three diseases mentioned above, according to the ICD-9-CM codes.…”

Section: Methodsmentioning

confidence: 99%

Clinical Characteristics of Hyperandrogenism Include Hirsutism, Polycystic Ovary Syndrome, and Acne: Association with Psychiatric Disease in Women -A Nationwide Population-Based Cohort Study in Taiwan

Wang¹,

Chou²,

Lee³

et al. 2022

IJWH

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Objective Previous studies have shown an increased in psychiatric disorders in women with disorders associated with hyperandrogenism, but few nationwide cohorts have studied this phenomenon. Therefore, this study is aimed to examine the association between the clinical manifestations of hyperandrogenism and subsequent psychiatric disorders. Methods Based on the National Health Insurance Research Database, 49,770 enrolled participants were matched for age and index date between January 1, 2000, and December 31, 2015. Hirsutism, polycystic ovary syndrome, and acne are characterized by hyperandrogenism. After adjusting for confounding factors, we used Cox proportional analysis to compare the risk of psychiatric disorders during the 16 years of follow-up. Results Of all the participants, 1319 (13.25%) had psychiatric disorders in the study group, whereas only 3900(9.80%) had psychiatric disorders in the control group. After adjusting for age, and monthly income, the Cox regression analysis showed that the study patients were more likely to develop psychiatric disorders (hazard ratio [HR]: 2.004, 95% confidence interval [CI] = 1.327–2.724, P < 0.001). The results demonstrated that women aged 20–29 years had a more significant risk. Conclusion Women with clinical characteristics of hyperandrogenism have a higher risk of developing psychiatric disorders, especially those aged 20–29 years.

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Risk of depression in patients with oral cancer: a nationwide cohort study in Taiwan

Cited by 12 publications

References 69 publications

Transcranial direct current stimulation in the treatment of anxiety and depression in patients with oral cancer during perioperative period

Transcranial direct current stimulation in the treatment of anxiety and depression in patients with oral cancer during perioperative period

Association Between Endometriosis and Mental Disorders Including Psychiatric Disorders, Suicide, and All-Cause Mortality -A Nationwide Population-Based Cohort Study in Taiwan

Clinical Characteristics of Hyperandrogenism Include Hirsutism, Polycystic Ovary Syndrome, and Acne: Association with Psychiatric Disease in Women -A Nationwide Population-Based Cohort Study in Taiwan

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