Background/purpose: Occlusion is an important component of temporomandibular joint (TMJ). Little is known about the association between missing teeth and TMJ changes. The purpose of this study was to determine if a correlation exists between unilateral missing posterior teeth and changes in the inclination of the articular eminence (AE). Materials and methods: A total of 106 joints in 53 patients (20 men and 33 women) with unilateral posterior edentulism were included. In the same patients, the sagittal outline of the AE and glenoid fossa was traced in panoramic radiographs. The sagittal condylar path inclination was constructed by joining the crest of the glenoid fossa and the crest of AE. This was then related to the constructed Frankfurt's horizontal plane to determine the inclination of AE. The results were subjected to the one-way analysis of variance test. A P value of <0.05 was considered to be statistically significant. Results: In this study 27% of the individuals were right posterior edentulous and 26% were left posterior edentulous. The mean value of AE inclination was 37.7 , ranging from 4 to 58 . A trend showing increased inclination angle in the nonmissing side compared with the missing side was observed (P > 0.05). The inclination of AE in men was higher than in women on both the missing side and the nonmissing side (P > 0.05). The symmetry equality between the missing and the nonmissing side joint was 1.89%. This value was higher (3%) in the female group Please cite this article in press as: Chiang M-T, et al., Evaluation of missing-tooth effect on articular eminence inclination of temporomandibular joint, Journal of Dental Sciences (2015), http://dx.Journal of Dental Sciences (2015) xx, 1e5than in the male group (0%). Comparing the absolute mean differences, the female group showed a lower difference (9.8 ) than the male group (12.11 ). Conclusion: A wide range of values of AE inclination was found regardless of other factors such as side of teeth loss and the sex of patients.

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This study investigates an association between oral cancers and the risk of developing depression. We conducted a total of 3031 patients with newly diagnosed oral cancers and 9093 age-, sex-, and index year-matched controls (1:3) from 2000 to 2013 were selected from the National Health Insurance Research Database (NHIRD) of Taiwan. After adjusting for confounding factors, multivariate Cox proportional hazards analysis was used to compare the risk of depression over a 13-year follow-up. Of the patients with oral cancer, 69 (2.28%, or 288.57 per 105 person-years) developed depression compared to 150 (1.65%, 135.64 per 105 person-years) in the control group. The Cox proportional hazards regression analysis showed that the adjustment hazard ratio (HR) for subsequent depression in patients with oral cancer diagnosed was 2.224 (95% Confidence Interval [CI] 1.641–3.013, p < 0.001). It is noteworthy that in the sensitivity analysis is the adjusted HR in the group with depression diagnosis was 3.392 and in the oral cancer subgroup of “Tongue” was 2.539. This study shows oral cancer was associated with a significantly increased risk for developing subsequent depression and early identification and treatment of depression in oral cancer patients is crucial.