Risk of stomach cancer incidence in a cohort of Mayak PA workers occupationally exposed to ionizing radiation

Zhuntova, G.V.; Azizova, Tamara V.; Grigoryeva, E. S.

doi:10.1371/journal.pone.0231531

Cited by 3 publications

(3 citation statements)

References 47 publications

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“…Like plutonium, radon emits alpha particles, suggesting there may be no association between groundwater radon and stomach cancer despite apparent biological plausibility. 24 Studies investigating the association between residential radon exposure and stomach cancer are reported in Table 2. In a small case-cohort study in Finland, risk of stomach cancer was not attributed to radon or other radionuclides in well water (HR:0.68; 95% CI:0.29, 1.59).…”

Section: Stomach Cancermentioning

confidence: 99%

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Residential radon exposure and cancer

Reddy¹,

Conde²,

Peterson³

et al. 2022

Oncol Rev

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Radon is an established human lung carcinogen naturally released as an odorless, colorless gas from soil and rocks. It is a major environmental source of ionizing radiation and can cause oxidative damage to DNA, increasing the risk of cancer. Although the association between radon and lung cancer is well established, the association between radon and other cancers is not. Based on reported studies, there is no consistent evidence indicating an association between radon and non-lung cancers, but limited literature, heterogenous study design, and confounding variables preclude definitive conclusions. More research is needed to evaluate the association between residential radon and non-lung cancers, particularly with regard to skin cancer, CNS cancer, and stomach cancer, in which existing literature suggests potential associations with residential radon may exist. However, the literature largely demonstrates that lung cancer is the primary concern associated with residential radon exposure and that non-lung cancers are secondary concerns. These results should be considered in residential radon mitigation efforts.

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Section: Stomach Cancermentioning

confidence: 99%

“…Like plutonium, radon emits alpha particles, suggesting there may be no association between groundwater radon and stomach cancer despite apparent biological plausibility. 24 …”

Section: Introductionmentioning

confidence: 99%

Residential radon exposure and cancer

Reddy¹,

Conde²,

Peterson³

et al. 2022

Oncol Rev

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“…The study was supported by FMBA of Russia within the framework of the Federal Target Program "Ensuring Nuclear and Radiation Safety for 2016-2020and for the Period up to 2030" (state contract No. 56.002.20.2 dated 02.06.2020.…”

Section: Epidemiological Studies сведения об авторахmentioning

confidence: 99%

Analysis of Cancer Incidence Among Employees of Siberian Group of Chemical Enterprises

et al. 2021

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Background. One of the main directions in the field of ensuring radiation safety of “nuclear legacy” facilities is the assessment of radiation effects and most significant radiogenic risks in employees of nuclear enterprises and their descendants.Objective. Analysis of the cancer incidence among employees of the Siberian Group of Chemical Enterprises (SGCE) exposed to ionizing radiation in the course of their professional activities.Material and Methods. The actual values and standardized estimated risks of developing cancer among the SGCE workers occupationally exposed to ionizing radiation were calculated using generally accepted methods based on the information of the regional medical dosimetry registry of Seversk Biophysical Research Center of FMBA, containing updated data on all SGCE employees diagnosed with cancer (period from 01.01.1950 to 31.12.2015 inclusive). The control group consisted of workers who were not occupationally exposed to ionizing radiation.Results. Among the male personnel of the SGCE, the highest incidence of cancer of the digestive, respiratory, and skin organs (including melanoma) was observed in patients aged 50–59 and 70–79 years. Among the female workers, the highest cancer incidence was in the age group 40–49 years; cancer of the gastrointestinal tract, genital tract and breast was the most common. The cancer incidence rate in the SGCE workers who occupationally exposed to ionizing radiation was not higher that that observed in the control group. The median age of male cancer patients occupationally exposed to ionizing radiation was significantly lower than the median age of male cancer patients of the control group. In female cancer patients, a significant difference in the median age of cancer diagnosis was found only in relation to skin cancer. Both male and female SGCE personnel occupationally exposed to ionizing radiation was at high risk of certain cancers: among male patients – cancer of the mesothelium and soft tissues, genital organs, eyes and brain, as well as multiple primary tumors; among female patients – cancer of lips, oral cavity, pharynx, digestive system, respiratory system, skin (including melanoma), mesothelium, soft tissues, breast, urinary tract, lymphatic and hematopoietic tissues, as well as multiple primary tumors.Conclusion. The data obtained will allow determination of the main directions for assessing the health risks of personnel of radiation hazardous facilities and the formation of a set of measures aimed at improving the system of protection and improving the health of workers at radiation hazardous enterprises and the extension of their working longevity.

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Radon and lung cancer: Current status and future prospects

Liu,

Xu,

et al. 2024

Critical Reviews in Oncology/Hematology

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Risk of stomach cancer incidence in a cohort of Mayak PA workers occupationally exposed to ionizing radiation

Cited by 3 publications

References 47 publications

Residential radon exposure and cancer

Residential radon exposure and cancer

Analysis of Cancer Incidence Among Employees of Siberian Group of Chemical Enterprises

Radon and lung cancer: Current status and future prospects

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