Risks and benefits of ending of mass screening for neuroblastoma at 6 months of age in Japan

Correlation between the number of segmental chromosome aberrations and the age at diagnosis of diploid neuroblastomas without MYCN amplification

“…Genome-wide high-resolution screening methods, such as single-nucleotide polymorphism (SNP) [8,9], comparative genomic hybridization (CGH) [10], and other arrays have recently been used to detect the biological alterations in NBs samples instead of low-resolution approaches such as Gbanded chromosome analysis. These genome-wide analyses have facilitated and accelerated the known copy number alterations of NBs.…”