Due to the intermittent and uncertainty nature of photovoltaic system, their incorporation within a DC microgrid presents a challenge to the primary control, which directly interfaces with the generation converter. Utilizing a weighted mix-sensitivity control, this study aims to amplify the robustness of a non-inverting buck-boost converter integrated photovoltaic system in addressing the uncertainties and disturbances arising from simultaneous fluctuations in irradiance, temperature, and load. The robust control algorithm was formulated by employing frequency-weighting functions and imposing a requirement for the minimum norm of the transformation matrix to accomplish a robust performance and robust stability. Furthermore, the involvement of reference models into a robust control synthesis offerred additional advantages in enhancing the damping of the system. Consequently, the entire design configuration could effectively establish the converter robustness against both generations and load intermittencies occurring simultaneously. The simulation and experiment result is demonstrated to illustrate the efficiency of the designed algorithm.