For years, soil-structure interaction (SSI) has been a subject of interdisciplinary studies, although full-scale SSI experiments and the use of real data are rare. To study SSI in a well-known and controlled environment, a full-scale experiment, EuroMASS, was conducted at the Piana di Toppo test site in Northeast Italy. For the needs of the experiment, a simple structure consisting of a lumped mass overtopping a steel column on a concrete base was designed and assembled at the test site. In April 2022, a three-component instrumentation network was installed to record the seismic noise, weak earthquake motions, and active source signals to study the structure, the foundation, and the soil seismic responses. The experiment was designed to collect data that can be used for accurate dynamic characterization of the structure and analysis of wave propagation in the soil-structure system.