Robust optimization in nanoparticle technology: A proof of principle by quantum dot growth in a residence time reactor

Methodology for the Computational Optimization of Nanoparticle Synthesis and Particle Size Distribution, Using Ir(0)n Nanoparticles as an Example System

“…Our approach differs in that we allow for arbitrary reaction dynamics and limit the mathematical expertise required to that of formulating differential equations from systems of chemical reactions. This approach matches the level of mathematical expertise in the nanoparticle community; more importantly, it is applicable to a far wider range of systems than the sophisticated approach of ref .…”

“…To the best of our knowledge, the work in ref is the only other detailed, mathematical approach in the literature addressing the experimental design of nanoparticle systems to achieve a desired outcome. The approach outlined in ref requires substantial mathematical sophistication and assumptions on the synthesis process (e.g., no agglomeration is taken into account). The result there is a clever formulation of the problem which can then be solved efficiently.…”