Robust, scalable construction of an electrophilic deuterated methylthiolating reagent: facile access to SCD₃-containing scaffolds

Abstract

We have established a practical and concise method to straightforward access a universal deuterated methylthiolating reagent through a one-pot gram-scale operation under mild conditions. This odourless electrophilic SCD3 reagent is...

Nickel(ii)-catalyzed highly selective 1,2-diborylation of non-activated monosubstituted alkenes

“…On the basis of the above results and related literature, 9,11,12 a plausible mechanism of this 1,2-diborylation process was proposed (using 1a and 2a as model substrate). The process is initiated with a Ni( ii ) species A , formed via transmetalation with B 2 pin 2 2a .…”

Construction of Non-Biaryl Atropisomeric Amide Scaffolds Bearing a C–N Axis via Enantioselective Catalysis

“…The transition metal-catalyzed cross-coupling reaction has emerged as one of the most effective methods for the construction of C–C and C–Heteroatom bonds from readily available feedstocks and has also found extensive utilization in organic synthesis [ 22 , 23 , 24 , 25 , 26 ]. The booming demand for chiral compounds in the chemical and pharmaceutical industries has continued to facilitate the advancement of practical catalytic methods for asymmetric transformation.…”

Organocatalytic atroposelective N-alkylation: divergent synthesis of axially chiral sulfonamides and biaryl amino phenols

“…Therefore, the cooperation of MBH acetate with the carbonate or phosphate anion could enable the selective N–H activation with the assistance of organocatalysis. 17…”