2017
DOI: 10.5455/jicm.24.259659
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ROLE OF ANTICARDIOLIPIN (aCL) ANTIBODIES IN BAD OBSTETRIC HISTORY (BOH) DETECTED BY ELISA TEST IN A TERTIARY CARE CENTRE

Abstract: The autoantibodies are present in 50% of patients with SLE and 1-5% of the general population. The antiphospholipid antibodies are found in serum in 1% of healthy persons and 3% of older age group (2). Though APS can involve any age group, the target group is young to middle aged adults. Depending upon the site of vascular obstruction, various symptoms occur in patients with APS. Interference in the balance between procoagulant and anticoagulant factors and disruption of the clotting mechanism by the antiphosp… Show more

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“…The algorithm of ELISA is based on the inhibition of the activity of certain enzymes (namely peroxidase and glucose oxidase) due to the interaction of the DPG-enzyme complex with antibodies. The use of cardiolipin Ag in the detection of antilipid antibodies by ELISA was proposed [ 35 ].…”
Section: Cardiolipin Antigen In Immunodiagnosticsmentioning
confidence: 99%
“…The algorithm of ELISA is based on the inhibition of the activity of certain enzymes (namely peroxidase and glucose oxidase) due to the interaction of the DPG-enzyme complex with antibodies. The use of cardiolipin Ag in the detection of antilipid antibodies by ELISA was proposed [ 35 ].…”
Section: Cardiolipin Antigen In Immunodiagnosticsmentioning
confidence: 99%