Role of Breast Ultrasound and Mammography in Evaluating Patients Presenting with Focal Breast Pain in the Absence of a Palpable Lump

Leddy, Rebecca; Irshad, Abid; Zerwas, Emily; Mayes, Nicholas; Armeson, Kent; Abid, Maham; Cluver, Abbie; Campbell, Amy; Ackerman, Susan; Lewis, Madelene

doi:10.1111/tbj.12178

Cited by 39 publications

(19 citation statements)

References 12 publications

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“…Mammography and ultrasonography demonstrate sensitivity rates of 85–88 % [4–7] and 93–97 % [7–10] for a general screening and diagnostic population, while the iBE in this population of known detectable findings demonstrated a comparable sensitivity of 85.7 %. The performance of this device meets the threshold of a pre-screening device when compared to the current pre-screening tool, CBE, which has a sensitivity of 50–60 % [11, 12].…”

Section: Discussionmentioning

confidence: 99%

A cost-effective handheld breast scanner for use in low-resource environments: a validation study

et al. 2016

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BackgroundWith the incidence of breast cancer rising worldwide, we are evaluating the iBreastExam (iBE) (UE LifeSciences Inc.), a handheld breast scanning device that can be utilized by community health workers to screen for breast abnormalities. The purpose of this study is to determine the sensitivity of the iBE in a population undergoing diagnostic breast imaging.MethodsAdult patients presenting to a breast imaging center for a diagnostic workup were eligible. Patients underwent an iBE exam performed by a trained ultrasound technician followed by their indicated imaging. Demographic, imaging, and biopsy data were recorded.ResultsSeventy-eight iBE exams were completed, 77 females and one male with a mean age of 42 (21–79). All patients were evaluated by ultrasound, 52 had diagnostic mammography and 39 had biopsies. Imaging and/or biopsy confirmed a mass (fibroadenoma, cyst, papilloma, myofibroblastoma, fat necrosis, DCIS, or cancer) in 60 patients. Twelve patients had a cancer diagnosed. In total, 342 quadrants were scanned, 77 quadrants had lesions confirmed on imaging, and iBE correctly identified 66 lesions for a sensitivity of 86 % and specificity of 89 %.ConclusionsThis validation study demonstrated excellent sensitivity of iBE for the identification of clinically significant lesions in patients presenting for diagnostic imaging.Trial registrationA Cost-Effective Handheld Breast Scanner for Use in Low Resource Environments: A Validation Study: NCT02814292.

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Section: Discussionmentioning

confidence: 99%

A cost-effective handheld breast scanner for use in low-resource environments: a validation study

et al. 2016

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“…Even though studies support the view that no strong relations exist between breast pain and breast cancer, the uneasiness and fear of breast cancer caused by pain are persistent (12,13). In assessing the relation of mastalgia with cancer, it is important to determine the type of mastalgia and to uncover the underlying reason for pain using other diagnostic tools in the ensuing period.…”

Section: Discussionmentioning

confidence: 99%

Mastalgia-Cancer Relationship: A Prospective Study

Yıldırım¹,

Yıldız²,

Yıldız³

et al. 2015

J Breasth Health

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Objective: Mastalgia is an important symptom affecting approximately 70% of women and it disrupts the quality of life especially due to the worry of having cancer. In our study, the type and severity of mastalgia symptom of patients who presented to the outpatient clinic with mastalgia complaint were assessed along with their physical examination findings and radiology results. The purpose of the study is to demonstrate the relationship between mastalgia and malignity when assessed in combination with the risk factors of patients. Materials and Methods:The age, family history, menopausal status, age at the first childbirth, menarche, presence/absence of hormone replacement therapy, type of mastalgia, comorbidities and examination findings of 104 patients, who presented to the General Surgery outpatient clinic with mastalgia symptom, were recorded and assessed in the light of radiological study results.Results: With respect to the mastalgia types of the patients, 38.5% had cyclic pain, 57.7% non-cyclic pain and 3.8% other types of pain. Mild mastalgia was present in 46.2% of the patients, moderate mastalgia in 24% and severe mastalgia in 29.8% of them. According to the BIRADS category, 48.1% of the patients were identified to have BIRADS 1 mass lesions, 39.4% BIRADS 2, 9.6% BIRADS 3 and 2.9% BIRADS 5 mass lesions. The patients who were identified to have BIRADS 5 mass lesions described non-cyclic and severe pain in the post-menopausal period. They had palpable masses along with the pain symptom. Conclusion:Our study suggests that mastalgia symptom does not per se result in suspicion of malignancy, but physical examination and radiological imaging should also be used as needed for confirmation. Studies with a larger patient population are needed to shed light on the mastalgia epidemiology and its relationship with cancer.

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“…Bu ça-lışmada MG'ye ek olarak meme US'u yapılmasının meme kanseri saptamadaki duyarlılığı artırıp artırmadığı konusu net olarak açıklığa kavuşturulmamakla birlikte, MG'si negatif ya da benign olan bir olguda US ile tespit edilebilen meme kanseri bildirilmemiştir. Meme ağrısı olan hastalarda MG'ye ek olarak yapı-lan US'un katkısını araştıran bir diğer çalışmada ise, benzer şe-kilde çalışmaya dahil edilen hastalarda MG'ye ek olarak yapı-lan US'un meme kanseri tanısında duyarlılığı artırmadığı bildirilmiştir [17]. Biz de çalışmamızı planlarken, özellikle mevcut literatür bilgisine ek veri sağlamak amacıyla, meme ağrısı şikayetiyle başvuran ve MG sonucu negatif (normal ya da benign ) olan hasta grubunda US incelemesinin katkısını ortaya koymayı amaçladık.…”

Section: Discussionunclassified

Role of Breast Ultrasound in Patients with Negative Mammogram Presenting with Breast Pain Without a Palpable Lump

Özan¹

2015

Ann Clin Anal Med

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ÖzetAmaç: Çalışmamızda meme ağrısı yakınmasıyla başvuran palpabl kitlesi bulunmayan olgularda mamografiye ek olarak yapılan meme ultrasonunun meme kanseri tanısında katkısı olup olmadığını araştırmayı amaçladık. Gereç ve Yöntem: Ocak 2012-Ocak 2013 tarihleri arasında meme ağrısı yakın-masıyla başvuran palpabl kitlesi bulunmayan olguların mamografileri retrospektif olarak incelendi. Mamografiye ek olarak meme ultrasonu incelemesi yapılan toplam 135 hasta görüntüleme bulguları, biyopsi sonuçları, klinik ya da radyolojik takip sonuçları açısından retrospektif olarak değerlendirildi. Ça-lışmamıza dahil edilen hasta grubunda mamografi ve ultrasonun meme kanseri tanısındaki güç ve yeterlilik analizi için yapılacak incelemeler öncesinde; mamografi ve ultrasonda Kategori 1,2,3 olan hastalar meme kanseri açısın-dan negatif olarak gruplandırılırken, mamografide kategorileri 0, 4 ve 5 olanlar pozitif, ultrasonda ise kategorileri 4 ve 5 olanlar pozitif olarak kabul edildi. Bulgular: Çalışmamızda negatif (normal ya da benign) mamografili olgularda ek olarak yapılan ultrason incelemesinin meme kanseri tanısında duyarlılığı artırmadığı saptanmıştır. Mamografi sonucu negatif olan olgularda ek olarak yapılan ultrason incelemesi, meme kanseri tanısında duyarlılığı artırmaksızın tüm grupta, 135 hastanın 14'ünde (% 10.3) kategoriyi yükseltmiştir. Tartış-ma: Mastalji ya da mastodini olarak da bilinen meme ağrısı kadınların yaklaşık % 70' ini hayatlarının bir döneminde etkileyen bir olumsuzluktur. Literatürde meme ağrısı ile başvuran palpabl kitlesi bulunmayan olgularda mamografiye ek olarak ultrason yapılmasının meme kanseri saptamadaki rolünü araştıran sınırlı sayıda çalışma mevcuttur. Bilgilerimize göre yapmış olduğu-muz çalışma bu konuda literatürdeki ilk çalışmalardandır. Mastaljili hasta popülasyonunda daha fazla katılımcı ile gerçekleştirilecek çalışmalar konu ile ilgili daha detaylı veriler sağlayacaktır. Anahtar KelimelerMastalji; Mamografi; Ultrason; Meme Kanseri Abstract Aim: To determine if addition of an ultrasound examination to mammography has an impact on detecting breast cancer in the patients who present with breast pain without a palpable lump. Material and Method: The mammography data from January 2008 to April 2011 was retrospectively reviewed for patients who presented with focal breast pain without a palpable lump. A total of 135 patients in which an ultrasound examination was performed in addition to mammography were retrospectively analyzed for their imaging findings and eventual outcome based on biopsy results, imaging follow-up, or clinical follow-up. For the purpose of test analysis, categories 1-3 were considered negative on mammography and ultrasound and categories 0, 4, and 5 were considered positive on mammography while categories 4 and 5 were considered positive on ultrasound. Results: The addition of an ultrasound examination in the presence of a normal or benign mammogram in the whole group upgraded the examination category in 14 (%10.3) of 135 cases without increasing the sensitivity for detection ...

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Role of Breast Ultrasound and Mammography in Evaluating Patients Presenting with Focal Breast Pain in the Absence of a Palpable Lump

Cited by 39 publications

References 12 publications

A cost-effective handheld breast scanner for use in low-resource environments: a validation study

A cost-effective handheld breast scanner for use in low-resource environments: a validation study

Mastalgia-Cancer Relationship: A Prospective Study

Role of Breast Ultrasound in Patients with Negative Mammogram Presenting with Breast Pain Without a Palpable Lump

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