Role of cardiovascular risk factors (CRF) in the patients with mild cognitive impairment (MCI)

Ettorre, Evaristo; Cerra, E; Marigliano, Benedetta; Vigliotta, M.; Vulcano, A.; Fossati, C; Benedetto, G. De; Servello, Adriana; Andrea, Paola; Marigliano, Vincenzo

doi:10.1016/j.archger.2011.04.025

Cited by 32 publications

(23 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Ettorre and colleagues reported that in a group of MCI patients, 60% of them eventually developed dementia, and all subgroups with cardiovascular risk factors had a higher conversion rate to AD 102. In addition, many cardiovascular risk factors occur in conjunction with each other, compounding the risk of subtle gray matter changes and subclinical cerebrovascular abnormalities in the brain, as well as dementia 103–106.…”

Section: Cardiovascular Risk Factorsmentioning

confidence: 99%

Heart disease as a risk factor for dementia

Ng¹,

Turek²,

Hakim³

2013

CLEP

117

View full text Add to dashboard Cite

As life expectancy lengthens, dementia is becoming a significant human condition in terms of its prevalence and cost to society worldwide. It is important in that context to understand the preventable and treatable causes of dementia. This article exposes the link between dementia and heart disease in all its forms, including coronary artery disease, myocardial infarction, atrial fibrillation, valvular disease, and heart failure. This article also explores the cardiovascular risk factors and emphasizes that several of them are preventable and treatable. In addition to medical therapies, the lifestyle changes that may be useful in retarding the onset of dementia are also summarized.

show abstract

Section: Cardiovascular Risk Factorsmentioning

confidence: 99%

Heart disease as a risk factor for dementia

Ng¹,

Turek²,

Hakim³

2013

CLEP

117

View full text Add to dashboard Cite

show abstract

“…In fact, a sizable literature has accumulated showing that many of the primary factors related to AD are also significantly related to MCI risk, including age [6–8], education [7,8], gender [7,8], APOE ε4 genotype [6,7], hypertension and heart disease [6,9,10], diabetes [11,12], and depression [6,12,13]. While there has been a surge in research over the last decade on the topic of MCI, there is a paucity of literature available on this construct among Hispanics residing within the U.S. [14].…”

Section: Introductionmentioning

confidence: 99%

Risk factors for mild cognitive impairment among Mexican Americans

O’Bryant

Johnson

Reisch

et al. 2013

Alzheimer's & Dementia

View full text Add to dashboard Cite

Background While a great deal of literature has focused on risk factors for Mild Cognitive Impairment (MCI), little published work examines risk for MCI among Mexican Americans. Methods Data from 1628 participants (non-Hispanic n= 1002; Mexican American n=626) were analyzed from two ongoing studies of cognitive aging and Alzheimer’s disease, Project FRONTIER and TARCC. Results When looking at the full cohorts (non-Hispanic and Mexican American), age, education, APOE ε4 status and gender were consistently related to MCI diagnosis across the two cohorts. However, when split by ethnicity advancing age was the only significant risk factor for MCI among Mexican Americans across both cohorts. Conclusions The current data suggests that many of the previously established risk factors for MCI among non-Hispanic cohorts may not be predictive of MCI among Mexican Americans and point to the need for additional work aimed at understanding factors related to cognitive aging among this underserved segment of the population.

show abstract

“…Psoriasis is also frequently associated with psychological distress and depression [6]. All of the aforementioned conditions likely confer to patients with psoriasis a high risk of developing major cardiovascular events including stroke and also cognitive impairment [7,8]. …”

Section: Introductionmentioning

confidence: 99%

Mild Cognitive Impairment in Patients with Moderate to Severe Chronic Plaque Psoriasis

Gisondi

Sala²,

Alessandrini³

et al. 2014

Dermatology

View full text Add to dashboard Cite

Background: Psoriasis is frequently associated with cardiometabolic comorbidities and depression that are risk factors for cognitive impairment. Objective: To investigate cognitive performance in psoriatic patients. Method: Cognitive performances were assessed by neuropsychological tests in 41 patients with psoriasis and 37 controls. Diagnostic criteria for mild cognitive impairment (MCI) were (1) subjective complaint of a memory deficit, confirmed by a relative or caregiver, (2) pathological performance on neuropsychological tests investigating cognitive domains, (3) normal performance of daily living activities and (4) no dementia. Neuroimaging was studied by high-field magnetic resonance imaging and cortical thickness analysis. Results: MCI was found in 18 out of 41 (44%) patients with psoriasis compared to 4 out of 37 (11%) controls (p = 0.002). In particular, patients with psoriasis had lower scores in the delayed recall of the Rey Auditory Verbal Learning Test (p = 0.04), Backwards Digit Span Test (p = 0.002), Weigl's Sorting Test (p = 0.01) and Trail Making Test B (p = 0.008). In the 7 patients submitted to cortical thickness analysis, a reduction in brain thickness in parahippocampal, superior temporal and frontal gyri of the left hemisphere was observed. Conclusions: Patients with psoriasis may have a precocious impairment of long-term verbal memory, executive functions and attention.

show abstract

Role of cardiovascular risk factors (CRF) in the patients with mild cognitive impairment (MCI)

Cited by 32 publications

References 17 publications

Heart disease as a risk factor for dementia

Heart disease as a risk factor for dementia

Risk factors for mild cognitive impairment among Mexican Americans

Mild Cognitive Impairment in Patients with Moderate to Severe Chronic Plaque Psoriasis

Contact Info

Product

Resources

About