Role of cerebral blood flow autoregulation in internal carotid artery stenosis surgery

Introduction. Slow fl uctuations in the volume and pressure of liquids in the cranial cavity have been known for a long time and have been studied for more than 100 years. However, their quantitative indicators and their practical signifi cance remain unclear until now due to the diffi culties of research. Nevertheless, it was found that they were connected with the brain activity, which made it possible to use them as one of the physiological indicators in studying the problems of manned space fl ights. Goal of research — to study the possibility of using spectral analysis of slow fl uctuations of the volume of liquids inside the cranium in order to realize the quantitative assessment of their indicators with the use of modern microelectronics and computer technology.Materials and methods. In order to solve this problem we created a complex, in which rheoencephalograph-RG-01 («Mizar») was used as a converter-modulator of physiological signals into electrical oscillations. The device was connected with the ADC (Firm «ADIstrument»), Its software allows to calculate the spectrogram with a sampling rate of 128 kHz. Studies were conducted on volunteers of younger, middle and older age groups. The respiratory rate and the electrocardiography were registered together with the rheoencephalography. Electrodes were fi xed on the volonteers′ fronto-mastoid area.Results. Slow fl uctuations the cranium representan independent physiological phenomenon. The most considerable and valuable were fl uctuations in 0,1–0,3 Hz. It was found that current frequency of 100 or 200 kHz and frequency for quantization of 80–100 kHz was optimal for performing their spectrograms. The structure of such diagram consists of 4–7 peaks with amplitude of 0,4–0,7 units compared with REG pulse amplitude. They depend on age and are characterized by hemispheric asymmetry. Spectral diagrams of slow fl ucation inside cranium are representing inpendent physiological phenomenon. These fl uctuations are not connected by common origin, with heart activity and respiration. They are connected by nature with brain activity and PRM.Conclusion. Can be an informative method for diagnostic and assessment of general status of osteopathic patients well as for the assessment of mechanisms of action of some osteopathic techniques.

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Quantitative evaluation of slow fluctuations of the volume of liquids inside cranial cavity

Moskalenko

Кравченко²,

Novozhilova

2019

Rossijskij osteopaticheskij zhurnal

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Changes in Cerebral Perfusion According to Single Photon Emission Computed Tomography after Coronary Artery Bypass Grafting and Simultaneous Interventions on the Carotid and Coronary Arteries

Короткевич

Семенов

Малева

et al. 2022

jour

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Goal of investigation was comparison and assessment of the state of cerebral perfusion according to SPECT data after coronary artery bypass grafting and simultaneous surgical intervention on the carotid and coronary arteries.Brain perfusion data were studied in 34 cardiac surgical patients who underwent surgical correction under conditions of cardiopulmonary bypass: simultaneous intervention on the coronary and carotid arteries (n = 21) and coronary artery bypass grafting (n = 13). The study of the brain was carried out by SPECT with the radiopharmaceutical 99mTc-HMPAO (Ceretek).In the group with CABG, there was a statistically significant decrease in the CBF values in the region of the caudate nucleus on the right, in both occipital and parietal lobes (p = 0.004193). In the group with simultaneous interventions, a significant decrease in the CBF indices in the right occipital and left parietal lobes (p = 0.020672), an increase in the indices in the left temporal lobe (p = 0.011286) was revealed.CBF indicators in the group with simultaneous interventions are significantly lower than those in the group with CABG both in the preoperative and postoperative periods.The data obtained indicate that patients with combined atherosclerotic lesions of the coronary and carotid arteries have significantly lower values of the CBF in comparison with patients with isolated changes in the coronary arteries.Coronary artery bypass grafting and simultaneous surgical interventions on the carotid and coronary arteries under cardiopulmonary bypass may be accompanied by a significant decrease in regional cerebral blood flow in certain areas of the brain, and these changes in the CABG group can be traced in a larger number of analyzed areas.

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Role of cerebral blood flow autoregulation in internal carotid artery stenosis surgery

Cited by 2 publications

References 30 publications

Quantitative evaluation of slow fluctuations of the volume of liquids inside cranial cavity

Quantitative evaluation of slow fluctuations of the volume of liquids inside cranial cavity

Changes in Cerebral Perfusion According to Single Photon Emission Computed Tomography after Coronary Artery Bypass Grafting and Simultaneous Interventions on the Carotid and Coronary Arteries

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