Role of chest ct scanning in the management of patients presenting with head and neck cancer

Houghton, David; Hughes, Monica A.; Garvey, C.J.; Beasley, Nigel; Hamilton, John; Gerlinger, Imre; Jones, A. S.

doi:10.1002/(sici)1097-0347(199810)20:7<614::aid-hed6>3.0.co;2-j

Cited by 71 publications

(7 citation statements)

References 21 publications

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“…This implies the possibility of detecting a second primary tumor while evaluating the presence of local or distant metastatic involvement of a malignant disease which is not uncommon due to the use of advanced screening modalities studies [15,16]. In group II patients, lung carcinoma was the most second concurrent malignancy.…”

Section: Discussionmentioning

confidence: 99%

Multiple Primary Tumors in Differentiated Thyroid Carcinoma and Relationship to Thyroid Cancer Outcome

et al. 2008

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Abstract. AIM: Patients with differentiated thyroid carcinoma (DTC) have long-life expectancy and are at risk for developing a second primary cancer. Aim of this study was to assess the occurrence of DTC in conjunction with other primary neoplasms. It was also aimed to explore the possibility of synchronous or metachronous other malignancies having an impact on clinical course of thyroid carcinoma. MATERIAL & METHODS: Clinical records of 1680 DTC patients treated and followed in our institution over last twenty years were reviewed. Forty-five second primary tumors were found in 42 patients. These patients were classified into 3 groups as antecedent (group I), synchronous (group II) or subsequent (group III) according to the timing of occurrence of non-thyroidal malignancy. The initial characteristics of thyroid neoplasm were compared between patients with DTC plus another tumor and DTC only. Kaplan-Meier Survival Analysis was used to estimate the survival probability for patients with DTC alone and DTC plus another primary tumor. RESULTS: There were 15 synchronous and 30 metachronous tumors in 42 patients. Three of them had triple tumors. The most common second primary was lympho-haematological and upper aero digestive system tumors in group I and II respectively, whereas a variety of tumors were noted in group III. Despite the more common occurrence of unfavourable prognostic factors in patients with multiple cancers than thyroid cancer alone, complete response to radioiodine therapy and recurrence free survival rate was similar in both groups (p>0.05). CONCLUSION: The results of the current series imply that the occurrence of multiple primary tumors is not uncommon in patients with DTC. Close medical surveillance and the use of advanced screening modalities might lead to the detection of second primary tumors in DTC. However, the presence of second primary seems not to affect the clinical course of DTC.

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Section: Discussionmentioning

confidence: 99%

Multiple Primary Tumors in Differentiated Thyroid Carcinoma and Relationship to Thyroid Cancer Outcome

et al. 2008

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“…[11,13,14,15] Other contributing factors to a higher prevalence are the inclusion of recurrent tumors and the selection of tumors more distally located such as in the hypopharynx and larynx. [9,10] When analyzing the 6 patients with a proven pulmonary malignancy of this study it appeared that none of these patients met the criteria of the guidelines of the Dutch Cooperative Head and Neck Oncology Group for a CT scan of the chest. [2,3] Recent lung cancer screening studies found a prevalence between 0.36% -2.7% at baseline screening, in a population with comparable risk on lung malignancies as our patient cohort.…”

Section: Incidence Of Secondary Pulmonary Tumorsmentioning

confidence: 95%

“…will show a higher incidence of pulmonary metastasis than one located more proximal such as in the oral cavity. [9,10] Also patients with locally advanced or recurrent tumor show more distant metastasis. [11,12,13,14,15,16] It is this riskassessment the guideline is based upon.…”

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confidence: 99%

Strategies for patients with newly diagnosed oral squamous cell carcinoma and a positive chest CT. A cohort study on the effects on treatment planning and incidence

Jaspers¹,

Witjes²,

Groen³

et al. 2011

European Journal of Surgical Oncology (EJSO)

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Please cite this article as: Jaspers GW, Witjes MJ, Groen HJ, Groen H, Rödiger LA, Roodenburg JL. Strategies for patients with newly diagnosed oral squamous cell carcinoma and a positive chest CT. A cohort study on the effects on treatment planning and incidence, European Journal of Surgical Oncology (2010Oncology ( ), doi: 10.1016Oncology ( /j.ejso.2010 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. In 20 (13%) patients chest abnormalities were observed on CT scan of the chest and in 6 (4%) patients malignancy was pathologically confirmed. Both pulmonary second primary tumors and pulmonary metastases were independent of stage of oral malignancy. We found that additional diagnostic procedures did not significantly lengthen the time interval between first consult and start of treatment. The cost of the screening for pulmonary malignancies in the group was € 8.214 per observed pulmonary malignancy.We advocate that CT imaging of the chest should be routinely performed in the diagnostic work up of all patients with a newly discovered SCC of the oral cavity, irrespective of the tumor stage of the oral malignancy.

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“…Современные методы диагностики злокачественных новообразований гортани К современным методам диагностики рака горта-ни, кроме общеклинического обследования, относят: прямую и непрямую ларингоскопии, микроларинго-скопию, стробоскопию, фиброларингоскопию, рент-геновское исследование, компьютерную томографию, мультиспиральную компьютерную томографию, маг-нитно-резонансную томографию, ультразвуковое ис-следование гортани и органов шеи, акустический анализ голоса, морфологические исследования [3][4][5][6][7][8][9][10][11][12][13][14][15][16]. Для диагностики и верификации злокачественного новообразования нельзя полагаться на результат одно-го метода диагностики, их следует применять комплек-сно, так как каждый имеет свои преимущества и недо-статки.…”

Section: Introductionunclassified

“…Однако встречаются трудности при интерпретации полученных результатов, так как не удается избежать двигательных артефактов, также эти методы исследования сопряжены с лучевой нагрузкой [3,4,6,8,11,13].…”

Section: Introductionunclassified

Current aspects of treatment and rehabilitation of patients with pharyngeal cancer

Kozhanov¹

2016

Opuholi golovy šei

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Role of chest ct scanning in the management of patients presenting with head and neck cancer

Cited by 71 publications

References 21 publications

Multiple Primary Tumors in Differentiated Thyroid Carcinoma and Relationship to Thyroid Cancer Outcome

Multiple Primary Tumors in Differentiated Thyroid Carcinoma and Relationship to Thyroid Cancer Outcome

Strategies for patients with newly diagnosed oral squamous cell carcinoma and a positive chest CT. A cohort study on the effects on treatment planning and incidence

Current aspects of treatment and rehabilitation of patients with pharyngeal cancer

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