Introduction: Acute pancreatitis is one of the most common diseases of the gastrointestinal tract. Imaging by CT scan helps in diagnosing severity of acute pancreatitis including the presence of pancreatic necrosis as well as local and systemic complications. Current study aimed to study the use of CT scan for the detection and evaluation of acute pancreatitis. Material and Methods: A total of 110 patients diagnosed clinically with acute pancreatitis were studied for patient demographics, clinical presentation, etiology and CT scan findings. Results: A ttal of 110 patients with age ranging from 15 years to 60 years were studied. The male to female ratio was 2.1:1. Most (59%) of the cases were in the 41 to 50 years age. Epigastric pain and vomiting were the most common clinical features. Gall stones and alcoholism were the most common etiological factors for acute pancreatitis. CT findings showed diffuse enlargement in 43.6% cases, and irregular contour in 63.6% cases. Ascites and pleural effusion were noted in 31.8% cases. Balthazar's CTSI system gave better results than the Ranson's criteria. Conclusion: Acute pancreatitis commonly affects adult males. CT scan plays an important role in diagnosing acute pancreatitis and Balthazar's CTSI system is advantageous over the Ranson's criteria system. The CT modality gives information on the severity and extent of the inflammatory process and thereby helps in decision making for patient management.