Role of electrostatic interactions in two-dimensional self-assembly of tobacco mosaic viruses on cationic lipid monolayers

Wang, Suntao; Fukuto, Masafumi; Checco, Antonio; Niu, Zhongwei; Wang, Qian; Yang, Lin

doi:10.1016/j.jcis.2011.03.048

Cited by 9 publications

(7 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…475 Parallel alignment of TMV can also be achieved through assembly at interfaces between buffer and a lipid monolayer supported on a submerged hydrophobic substrate, with the inclusion of Ca 2+ ions helping to screen Coulomb repulsion between the particles. 522, 523 Another possibility for the formation of assemblies of high aspect ratio viruses is through mixtures with spheres; the increased free energy at the interface favors the assembly of uniform structures. 524, 525 This was observed in a study where isotropic, nematic, lamellar, and crystalline phases were obta ined through the modulation of the concentration of TMV, the concentration of BSA or PEG spheres, and the ionic strength.…”

Section: Applications Of Virus-based Particlesmentioning

confidence: 99%

Design of virus-based nanomaterials for medicine, biotechnology, and energy

2016

View full text Add to dashboard Cite

Virus-based nanomaterials are versatile materials that naturally self-assemble and have relevance for a broad range of applications including medicine, biotechnology, and energy. This review provides an overview of recent developments in “chemical virology.” Viruses, as materials, provide unique nanoscale scaffolds that have relevance in chemical biology and nanotechnology, with diverse areas of applications. Some fundamental advantages of viruses, compared to synthetically programmed materials, include the highly precise spatial arrangement of their subunits into a diverse array of shapes and sizes and many available avenues for easy and reproducible modification. Here, we will first survey the broad distribution of viruses and various methods for producing virus-based nanoparticles, as well as engineering principles used to impart new functionalities. We will then examine the broad range of applications and implications of virus-based materials, focusing on the medical, biotechnology, and energy sectors. We anticipate that this field will continue to evolve and grow, with exciting new possibilities stemming from advancements in the rational design of virus-based nanomaterials.

show abstract

Section: Applications Of Virus-based Particlesmentioning

confidence: 99%

Design of virus-based nanomaterials for medicine, biotechnology, and energy

2016

View full text Add to dashboard Cite

show abstract

“…These counter-ion-induced attractions also have significant effects on the self-assembly of viruses with other materials. 146,147…”

Section: Ion Induced Virus Assemblymentioning

confidence: 99%

“…Recently, taking advantage of a substrate-supported fluid lipid monolayer, Yang et al achieved 2D assembly of TMV on a lipid surface. 146,147 TMV oriented along the interface and aligned parallel to their neighbors due to its rod-like shape. Detailed GISAXS study showed that higher charge densities resulted in poorer structural order for faster adsorption kinetics; meanwhile higher lipid-charged densities also contributed to higher TMV packing density.…”

Section: Assembly Of Virus With Dendrons Kostiainen Et Almentioning

confidence: 99%

Natural supramolecular building blocks: from virus coat proteins to viral nanoparticles

et al. 2012

Self Cite

View full text Add to dashboard Cite

Viruses belong to a fascinating class of natural supramolecular structures, composed of multiple copies of coat proteins (CPs) that assemble into different shapes with a variety of sizes from tens to hundreds of nanometres. Because of their advantages including simple/economic production, well-defined structural features, unique shapes and sizes, genetic programmability and robust chemistries, recently viruses and virus-like nanoparticles (VLPs) have been used widely in biomedical applications and materials synthesis. In this critical review, we highlight recent advances in the use of virus coat proteins (VCPs) and viral nanoparticles (VNPs) as building blocks in self-assembly studies and materials development. We first discuss the self-assembly of VCPs into VLPs, which can efficiently incorporate a variety of different materials as cores inside the viral protein shells. Then, the self-assembly of VNPs at surfaces or interfaces is summarized. Finally, we discuss the co-assembly of VNPs with different functional materials (178 references).

show abstract

“…From the relative intensities of the (21) peak and the adjacent peak on each side, we estimate that the contribution of the rhombic phase to the crystalline area is $25% or less at the TYMV concentration of 0.015 mg ml À1 while it becomes comparable to the rectangular contribution at 0.045 mg ml À1 . Since fast adsorption tends to impede 2D ordering, 28,36 the rhombic crystal may be a metastable phase.…”

Section: X-ray Scatteringmentioning

confidence: 99%

Crystallization, structural diversity and anisotropy effects in 2D arrays of icosahedral viruses

et al. 2013

Self Cite

View full text Add to dashboard Cite

We investigate two-dimensional (2D) assembly of the icosahedral turnip yellow mosaic virus (TYMV) under cationic lipid monolayers at the aqueous solution–vapor interface. The 2D crystallization of TYMV has been achieved by enhancing electrostatically induced interfacial adsorption, an approach recently demonstrated for another virus. In situ X-ray scattering reveals two close-packed 2D crystalline phases of TYMV that are distinct from the previously reported hexagonal and centered square ( 2×2) arrays of TYMV. One of the newly observed phases arises from either a dimeric double-square (2 × 1) or tetrameric square (2 × 2) unit cell. The other is a rhombic crystal with a lattice angle of 80°. The two observed crystal phases are substantially less dense (by over10%) than a 2D lattice of TYMV could be according to its known size and shape, indicating that local anisotropic interparticle interactions play a key role in stabilizing these crystals. TYMV’s anisotropy attributes and numerical analysis of 2D arrays of virus-shaped particles are used to derive a model for the rhombic crystal in which the particle orientation is consistent with the electrostatic lipid–TYMV attraction and the interparticle contacts exhibit steric complementarity. The interplay between particle anisotropy and packing is contrasted between the rhombic crystal model and the square ( 2×2) crystal. This study highlights how the high symmetry and subtle asphericity of icosahedral particles enrich the variety and complexity of ordered 2D structures that can be generated through self-assembly.

show abstract

Role of electrostatic interactions in two-dimensional self-assembly of tobacco mosaic viruses on cationic lipid monolayers

Cited by 9 publications

References 40 publications

Design of virus-based nanomaterials for medicine, biotechnology, and energy

Design of virus-based nanomaterials for medicine, biotechnology, and energy

Natural supramolecular building blocks: from virus coat proteins to viral nanoparticles

Crystallization, structural diversity and anisotropy effects in 2D arrays of icosahedral viruses

Contact Info

Product

Resources

About