Role of fine‐needle aspiration cytology in the prompt diagnosis of recurrence of visceral leishmaniasis presented as isolated cervical leishmanial lymphadenopathy

Abstract

We report a case of isolated cervical leishmanial lymphadenopathy diagnosed by fine-needle aspiration cytology (FNAC) in apparently cured case of visceral leishmaniasis. A 28-year-old female presented with cervical lymphnode enlargement to surgery outpatient department and was subjected for FNAC. Smear showed numerous Leishmania donovani bodies in the cytoplasm of macrophages and giant cells, and extracellular spaces. She was treated by Amphotericin B for alternate 14 days and the size of the lymphnode regressed. She was found asymptomatic for 1 year of follow-up.

Fine-needle aspiration cytology of leishmanial lymphadenitis in an HIV-reactive patient: Report of a rare case

“…Sometimes, other infectious agents such as Toxoplasma , Histoplasma , Paracoccidioides , and Cryptococcus may be morphologically misinterpreted as LD bodies in lymph node aspirates. [ 5 7 8 ] These differential diagnoses are important in cytological evaluation of lymph node aspirates in HIV patients.…”

“…Amphotericin B has been found to be more effective and less toxic than others in the treatment of visceral leishmaniasis with immunosuppression. [ 8 ]…”

Comments and illustrations of the WFUMB CEUS liver guidelines: Rare focal liver lesion – infectious parasitic, fungus

“…If visceral leishmaniasis is clinically suspected, microscopic detection of the pathogen in bone marrow is the method of choice. The pathogen can be directly detected through biopsy of the infected tissue, which is conducted by examining the bone marrow needle aspirates or from other affected organs with evidence of Leishmania amastigotes [79,84,[87][88][89]. Alternatively, PCR from peripheral blood or serological diagnostics can be used [83].…”