Role of HSF1-upregulated AC6 in ameliorating heart failure in mice

Du, Peizhao; Chang, Yaowei; Dai, Fangjie; Wei, Chunyan; Li, Jiming

doi:10.1016/j.etap.2016.08.015

Cited by 3 publications

(1 citation statement)

References 25 publications

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“… 11 In cardiovascular aspect, HSF1 can alleviate heart failure by actively regulating the AC6/cAMP/PKA pathway in a pressure overload heart failure model. 12 In addition, HSF1 can reduce myocardial cell damage and ultimately decrease the risk of heart failure. 13 However, more details about the mechanism of HSF1 in cardioprotection are still lacking.…”

Section: Introductionmentioning

confidence: 99%

Aberrant HSF1 signaling activation underlies metformin amelioration of myocardial infarction in mice

Wang¹,

Zou²,

Wang³

et al. 2022

Molecular Therapy - Nucleic Acids

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Section: Introductionmentioning

confidence: 99%

Aberrant HSF1 signaling activation underlies metformin amelioration of myocardial infarction in mice

Wang¹,

Zou²,

Wang³

et al. 2022

Molecular Therapy - Nucleic Acids

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The Human Costs of Terrorism

Solomon

2024

The Spectre of Islamic Terrorism: Comparative Insights

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Living in Mosul during the time of ISIS and the military liberation: results from a 40-cluster household survey

2018

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BackgroundIn June 2014, an estimated 1500 fighters of the Islamic State of Iraq and Syria (ISIS) seized control of Mosul, Iraq’s second city. Although many residents fled, others stayed behind, enduring the restrictive civil and social policies of ISIS. In December 2016, the military activity, known as the liberation campaign, began in east Mosul, concluding in west Mosul in June 2017.MethodsTo assess life in Mosul under ISIS, and the consequences of the military campaign to retake Mosul we conducted a 40 cluster-30 household survey in Mosul, starting in March 2017. All households included were present in Mosul throughout the entire time of ISIS control and military action.ResultsIn June 2014, 915 of 1139 school-age children (80.3%) had been in school, but only 28 (2.2%) attended at least some school after ISIS seized control. This represented a decision of families. Injuries to women resulting from intimate partner violence were reported in 415 (34.5%) households. In the surveyed households, 819 marriages had occurred; 688 (84.0%) among women. Of these women, 89 (12.9%) were aged 15 years and less, and 253 (49.7%) were aged under 18 at the time of marriage. With Mosul economically damaged by ISIS control and physically during the Iraqi military action, there was little employment at the time of the survey, and few persons were bringing cash into households. The liberation of Mosul in 2017 caused extensive damage to dwellings. Overall only a quarter of dwellings had not sustained some damage. In west Mosul, only 21.7% of houses had little or no damage from the conflict, with 98 (21.7%) households reporting their house had been destroyed, forcing its occupants to move. No houses had regular electricity and there was limited piped water. Inadequate fuel for cooking was reported by 996 (82.9%) households.ConclusionThe physical, and social damage occurring during ISIS occupation of Mosul and during the subsequent military action (liberation) was substantial and its impact is unlikely to be erased soon.

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Role of HSF1-upregulated AC6 in ameliorating heart failure in mice

Cited by 3 publications

References 25 publications

Aberrant HSF1 signaling activation underlies metformin amelioration of myocardial infarction in mice

Aberrant HSF1 signaling activation underlies metformin amelioration of myocardial infarction in mice

The Human Costs of Terrorism

Living in Mosul during the time of ISIS and the military liberation: results from a 40-cluster household survey

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