Role of image guided fine needle aspiration cytology in diagnosis of hepatic lesions-study at a tertiary care centre of Kashmir valley

Yasin, Syed Besina; Bashir, Nadia; Samoon, Nuzhat

doi:10.21276/apjhs.2017.4.2.32

Cited by 3 publications

(4 citation statements)

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“…They reported ages ranging from 12-90 years, and the maximum number of cases was in age group of 51-60 years. Similar results were obtained in the study by Rasania et al Yasin et al and Meena et al[13][14][15] …”

supporting

confidence: 90%

Fine Needle Aspiration Cytology with the Assistance of Radiological Tools in the Diagnosis of Deep-Seated Lesions

Dhakal

Makaju

Karki

et al. 2021

Kathmandu Univ. Med. J.

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Background Fine needle aspiration (FNA) with radiological assisted tools such as ultrasonography (USG) and computed tomography (CT) are effective in obtaining high yield aspiration of tissues located in technically difficult places such as deep-seated. It is a simple outpatient procedure with low cost as compared to surgical biopsies. Objective To study the cytomorphological features of deep-seated lesions according to the site of occurrence, and to categorize them with respect to age, sex and behavior of lesions. Method This was a descriptive cross-sectional study of 125 patients who underwent image-guided fine needle aspiration cytology of deep-seated lesions. The study was conducted in the Department of Pathology and Department of Radiodiagnosis, Dhulikhel Hospital- Kathmandu University Hospital, between January 2017 and December 2018. Under radiological guidance, aspiration was performed under negative pressure, and adequate material was obtained. Smears were stained with Giemsa and Papanicolaou stain. The prepared slides were examined under a microscope. Result Of the 125 patients who underwent USG and CT-guided fine needle aspiration cytology (FNAC), 68(54.4%) were female and 57(45.6%) were male. The age of the patients ranged from 13 to 84 years. The maximum number of patients was above 50 years. The nature of lesions was categorized as malignant 78(62.4%), followed by 23(18.4%) inflammatory and benign 1(0.8%). Conclusion Image-guided fine needle aspiration cytology is a safe diagnostic procedure, as it provides real-time visualization of tip insertion in anatomical structures. It provides high yield and a better representation of the samples.

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supporting

confidence: 90%

Fine Needle Aspiration Cytology with the Assistance of Radiological Tools in the Diagnosis of Deep-Seated Lesions

Dhakal

Makaju

Karki

et al. 2021

Kathmandu Univ. Med. J.

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“…Overall diagnostic accuracy was 98.85%. [1][2][3][4] The youngest patient as observed in present study is of 19 years and diagnosed as Hepatoblastoma. Similar observation has been made in the studies of Singh et al, Khanna et al, and Tailor and Kothari.…”

Section: Resultsmentioning

confidence: 99%

“…1 Their diagnostic evolution holds the key for institution of therapy, prognosis vis-a-vis staging of malignant neoplasm. 2 The ultrasound guided fine needle aspiration cytology in recent years have paved the way for diagnostic assessment of such SOL of high accuracy, sensitivity and specificity. [3][4][5][6][7] There are areas where fine needle aspiration cytology requires attention in avoidance of false diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Ultrasound guided fine needle aspiration cytology of space occupying lesions of liver

Rastogi¹,

Bhake

Agarwal

et al. 2018

Int J Res Med Sci

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Background: The liver is a common site for primary and secondary tumors; most often from malignant tumors within the abdomen and from extra-abdominal primary malignant neoplasm, but also for sarcomas and lymphomas. The main indication of fine-needle aspiration cytology (FNAC) of the liver is diagnosis of single or multiple space occupying lesions. This study aims to evaluate the cyto-morphology of primary and secondary neoplasms of liver and non-neoplastic conditions in the smears of ultrasound guided fine needle aspiration of SOL of liver, to evaluate the cytomorphologic features and to evaluate the erroneous diagnosis when compared with cell block preparation of aspirate (tissue diagnosis).Methods: This study is hospital-based prospective study including 57 patients with space occupying lesion of the liver mass. FNAC were carried out under the guidance of sonography and/or computed tomography. The staining performed were conventional for smears of the aspirate. The cell blocks were prepared from the aspirates by the established procedures. The values of correlation were bought out.Results: Males predominated over females. The distribution of cases for cyto-diagnosis were as follows; cirrhosis with hepatic granulosa (3 cases),pyogenic abscess (3 cases), hepatic adenoma (2 cases), Focal nodular hyperplasia (2 cases), hepatoblastoma (1 case), hepatocellular carcinoma (17 cases), adenocarcinoma deposits (20 cases), deposits of small cell carcinoma (3 cases), deposits of ductal carcinoma (2 cases) and 1 case each of deposits of squamous cell carcinoma, non-Hodgkin’s lymphoma, neuroendocrine tumor and adeno-squamous carcinoma. Values of correlation were as follows: sensitivity 97.61%, specificity 100%, PPV 100%, NPV 97.82% and diagnostic accuracy of 98.85%.Conclusions: FNAC is concluded to be first rank diagnostic procedure in diagnosis of SOL of liver of varied etiology with high values of NPV and PPV. It is also concluded that it helps in staging of metastatic malignancies.

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“…A study by Yasin et al was closest to ours amongst benign/ non neoplastic lesions. 34 We found HCC to be the most common primary malignancy (31/118) i.e. 26 % of all malignant lesions.…”

Section: Resultsmentioning

confidence: 75%

Guided FNAC of nodular lesions in liver

Jha¹,

Gupta²,

Pangarkar³

et al. 2020

ACHR

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Introduction:A focal mass or a nodule in the liver has become easily accessible to the needle of a pathologist, courtesy the rising numbers of guided FNAC. Precise localisation of lesions helps in studying the cytological features in greater detail, of the area in question. A targeted needle aspiration achieves high rates of sensitivity and specificity with regard to the varied spectrum of the pathologies encountered in liver especially when correlated with serological tests. Thus present study was carried out with aim to assess the role of guided FNAC in the diagnosis of nodular lesions of liver and to study their cytomorphology. Materials and Methods: It is an observational, prospective study of 130 adequate aspirates from liver nodules done at tertiary care hospital over two year period. All patients presenting with nodular liver mass detected on imaging techniques were selected for FNAC under USG or CT guidance. Another pass was taken from the surrounding liver to ascertain the presence of parenchymal changes like fatty change, cirrhosis and dysplasia. Results: Adequate aspirates from 130 cases were studied. Lesions were categorised into non neoplastic (11) and neoplastic which were further classified benign (1), primary malignancies (31HCC, 4 cholangiocarcinoma) metastasis ( 72) and undifferentiated malignancies (11) respectively on cytology. Conclusion: Guided FNAC of the liver is a rapid simple and precise method of identifying the pathology in liver nodules. It can be a useful modality to triage the patients and decide further line of management.

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Role of image guided fine needle aspiration cytology in diagnosis of hepatic lesions-study at a tertiary care centre of Kashmir valley

Cited by 3 publications

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Fine Needle Aspiration Cytology with the Assistance of Radiological Tools in the Diagnosis of Deep-Seated Lesions

Fine Needle Aspiration Cytology with the Assistance of Radiological Tools in the Diagnosis of Deep-Seated Lesions

Ultrasound guided fine needle aspiration cytology of space occupying lesions of liver

Guided FNAC of nodular lesions in liver

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