Role of Inulin in the Protection and Management of Metabolic Inflammation in Humans

Abstract

Systemic inflammation describes certain metabolic alterations which are mediated by inflammatory cytokines. Theses occur essentially as a defensive body response towards offending agents such as surplus nutrient staffs. Our aim is to find out the role of inulin as a protective agent against metabolic inflammation. Twenty eight type 2 diabetic females were subjected to the estimation of their serum high sensitivity C-reactive protein, lipopolysaccharides, tumor necrosis factor alpha, adiponectin and HOMA-IR test before and after three weeks of inulin ingestion. There was a significant drop in the level of serum high sensitivity C-reactive protein, lipopolysaccharides, tumor necrosis factor alpha, HOMA-IR and a non-significant rise in serum adiponectin after inulin ingestion. In summary inulin can act as a useful protective agent in systemic inflammation.